Suppr超能文献

精神分裂症患者面部表情识别障碍的矫治:一项新训练计划的疗效与特异性

Remediation of impairments in facial affect recognition in schizophrenia: efficacy and specificity of a new training program.

作者信息

Wölwer Wolfgang, Frommann Nicole, Halfmann Sabine, Piaszek Anja, Streit Marcus, Gaebel Wolfgang

机构信息

Department of Psychiatry and Psychotherapy, University of Duesseldorf, Rhineland State Clinics, Bergische Landstrasse 2, D-40629 Duesseldorf, Germany.

出版信息

Schizophr Res. 2005 Dec 15;80(2-3):295-303. doi: 10.1016/j.schres.2005.07.018. Epub 2005 Aug 24.

Abstract

OBJECTIVE

Schizophrenia patients often exhibit impairments in facial affect recognition which contribute to their poor social functioning. These impairments are stable in the course of the disorder and seem not to be affected by conventional treatment. The present study investigates the efficacy and specificity of a new training program for the remediation of such impairments.

METHOD

A newly developed training program tackling affect recognition (TAR) was compared with a cognitive remediation training program (CRT) and treatment as usual (TAU) within a randomized three group pre-post design in n=77 post-acute schizophrenia patients. The TAR is a computer-aided 12-session program focussing on facial affect recognition, whereas the CRT aims to improve attention, memory and executive functioning. Facial affect recognition, face recognition, and neurocognitive performance were assessed before (T0) and after (T1) the six week training phase. During the training period all patients received antipsychotic medication.

RESULTS

Patients under TAR significantly improved in facial affect recognition, with recognition performance after training approaching the level of healthy controls from former studies. Patients under CRT and those without special training (TAU) did not improve in affect recognition, though patients under CRT improved in verbal memory functions.

CONCLUSION

According to these results, remediation of disturbed facial affect recognition in schizophrenia patients is possible, but not achievable with a traditional cognitive rehabilitation program such as the CRT. Instead, functional specialized remediation programs such as the newly developed TAR are a more suitable option.

摘要

目的

精神分裂症患者常常在面部表情识别方面存在缺陷,这导致他们社交功能较差。这些缺陷在疾病过程中较为稳定,且似乎不受传统治疗的影响。本研究调查一种针对改善此类缺陷的新训练项目的疗效和特异性。

方法

在一项随机三组前后测设计中,将新开发的针对表情识别的训练项目(TAR)与认知康复训练项目(CRT)及常规治疗(TAU)进行比较,研究对象为77例急性后期精神分裂症患者。TAR是一个为期12节的计算机辅助项目,专注于面部表情识别,而CRT旨在改善注意力、记忆力和执行功能。在为期六周的训练阶段之前(T0)和之后(T1)评估面部表情识别、面孔识别和神经认知表现。在训练期间,所有患者均接受抗精神病药物治疗。

结果

接受TAR训练的患者在面部表情识别方面有显著改善,训练后的识别表现接近以往研究中健康对照组的水平。接受CRT训练的患者和未接受特殊训练(TAU)的患者在表情识别方面没有改善,不过接受CRT训练的患者在言语记忆功能方面有所改善。

结论

根据这些结果,精神分裂症患者受干扰的面部表情识别缺陷是可以改善的,但传统的认知康复项目如CRT无法实现这一点。相反,功能专门化的康复项目如新开发的TAR是更合适的选择。

文献AI研究员

20分钟写一篇综述,助力文献阅读效率提升50倍。

立即体验

用中文搜PubMed

大模型驱动的PubMed中文搜索引擎

马上搜索

文档翻译

学术文献翻译模型,支持多种主流文档格式。

立即体验