Awad J N, Kebaish K M, Donigan J, Cohen D B, Kostuik J P
Department of Orthopaedic Surgery, Johns Hopkins Bayview Medical Center, 4940 Eastern Avenue, A672, Baltimore, Maryland 21224, USA.
J Bone Joint Surg Br. 2005 Sep;87(9):1248-52. doi: 10.1302/0301-620X.87B9.16518.
In order to identify the risk factors and the incidence of post-operative spinal epidural haematoma, we analysed the records of 14 932 patients undergoing spinal surgery between 1984 and 2002. Of these, 32 (0.2%) required re-operation within one week of the initial procedure and had an International Classification of Diseases (ICD)-9 code for haematoma complicating a procedure (998.12). As controls, we selected those who had undergone a procedure of equal complexity by the same surgeon but who had not developed this complication. Risks identified before operation were older than 60 years of age, the use of pre-operative non-steroidal anti-inflammatories and Rh-positive blood type. Those during the procedure were involvement of more than five operative levels, a haemoglobin < 10 g/dL, and blood loss > 1 L, and after operation an international normalised ratio > 2.0 within the first 48 hours. All these were identified as significant (p < 0.03). Well-controlled anticoagulation and the use of drains were not associated with an increased risk of post-operative spinal epidural haematoma.
为了确定术后脊髓硬膜外血肿的危险因素和发生率,我们分析了1984年至2002年间14932例接受脊柱手术患者的记录。其中,32例(0.2%)在初次手术后一周内需要再次手术,且有国际疾病分类(ICD)-9编码表示手术并发血肿(998.12)。作为对照,我们选择了由同一位外科医生进行同等复杂程度手术但未发生此并发症的患者。术前确定的风险因素为年龄大于60岁、术前使用非甾体类抗炎药和Rh阳性血型。术中的风险因素为手术节段超过5个、血红蛋白<10 g/dL、失血量>1 L,术后48小时内国际标准化比值>2.0。所有这些均被确定为具有显著性(p<0.03)。良好控制的抗凝治疗和引流的使用与术后脊髓硬膜外血肿风险增加无关。