Agrawal Rahul Sudhir, Kothari Ajay Ramesh, Aiyer Siddharth Narasimhan, Sancheti Parag Kantilal
Department of Orthopaedics, Sancheti Institute of Orthopaedics and Rehabilitation, Pune, Maharashtra, India.
J Orthop Case Rep. 2025 Aug;15(8):56-60. doi: 10.13107/jocr.2025.v15.i08.5882.
Spontaneous spinal hemorrhage in dengue fever is extremely rare. We report a case of post-operative microdiscectomy complicated by delayed (>72 h) spontaneous lumbar epidural hematoma leading to cauda equina syndrome, having severe thrombocytopenia with dual viral infection (dengue and chikungunya) in a known case of chronic lymphoid leukemia (CLL). The patient was managed with transfusion of platelets followed by revision surgery with the evacuation of hematoma with lumbar decompression, following which the patient improved gradually. Although cases of symptomatic spinal epidural hematoma and post-viral infection have been reported, post-microdiscectomy together with CLL is not reported in literature.
A 62-year-old male with known hypertension and CLL presented with severe low back pain and left anterior thigh radiation, who underwent uneventful microscopic discectomy for L2-L3 disc sequestration. On post-operative day 4, the patient developed cauda equina syndrome with concurrent dengue and chikungunya infections, and magnetic resonance imaging revealed an extradural hematoma at L3-L5 level. After medical optimization with platelet transfusions and steroids, the patient underwent emergency surgical evacuation of the hematoma.
In post-operative microdiscectomy, delayed spontaneous spinal hematoma with cauda equina syndrome having dual viral fever (dengue and chikungunya) with CLL is a rare complication. Failure to recognize can lead to devastating outcomes with permanent neurological impairment. Prompt medical optimization following close clinico-serological monitoring with early surgical evacuation is needed. Early diagnosis with intervention can significantly improve the neurological outcome.
登革热患者出现自发性脊髓出血极为罕见。我们报告一例接受显微椎间盘切除术后的病例,该病例并发延迟性(>72小时)自发性腰段硬膜外血肿,导致马尾综合征,患者患有严重血小板减少症,并在慢性淋巴细胞白血病(CLL)已知病例中合并双重病毒感染(登革热和基孔肯雅热)。患者先接受血小板输注治疗,随后进行翻修手术,清除血肿并行腰椎减压,术后患者逐渐康复。虽然有症状性脊髓硬膜外血肿和病毒感染后的病例报告,但显微椎间盘切除术后合并CLL的情况在文献中未见报道。
一名62岁男性,患有高血压和CLL,因严重腰痛及左大腿前侧放射性疼痛就诊,因L2-L3椎间盘游离行显微椎间盘切除术,手术过程顺利。术后第4天,患者出现马尾综合征,同时合并登革热和基孔肯雅热感染,磁共振成像显示L3-L5水平硬膜外血肿。在通过输注血小板和使用类固醇进行医疗优化后,患者接受了血肿紧急手术清除。
在显微椎间盘切除术后,并发双重病毒热(登革热和基孔肯雅热)及CLL的延迟性自发性脊髓血肿伴马尾综合征是一种罕见的并发症。未能识别可能导致永久性神经功能损害的灾难性后果。需要在密切临床血清学监测下迅速进行医疗优化,并尽早进行手术清除。早期诊断并干预可显著改善神经功能预后。