Takeuchi D, Nakanishi T, Tomimatsu H, Nakazawa M
Department of Pediatric Cardiology, The Heart Institute of Japan, Tokyo Women's Medical University, Tokyo, Japan.
Pediatr Cardiol. 2006 Jan-Feb;27(1):78-83. doi: 10.1007/s00246-005-1023-3.
Right ventricular (RV) dysfunction may occur in patients after the atrial switch operation for d-transposition of the great arteries (d-TGA) and can be an important complication. Noninvasive assessment of RV function using echocardiography is necessary for following up these patients. We evaluated RV function using the Doppler Tei index (RV Tei index). The RV Tei index measures the ratio of total time intervals in isovolumetric contraction and relaxation to the ejection time. The subjects consisted of 33 patients who had undergone the atrial switch operation for d-TGA (the atrial switch group) (mean age, 21 +/- 4 years), 10 patients with pulmonary artery stenosis after the arterial switch operation for d-TGA (the arterial switch group) (mean age, 17 +/- 1 years), and 10 patients with a normally structured heart as a control group (mean age, 26 +/- 7 years). The RV Tei index (0.65 +/- 0.16) was significantly higher in the atrial switch group than in the arterial switch group (0.29 +/- 0.07) and the control group (0.29 +/- 0.01) (p < 0.05). The fractional area change of the RV obtained from the four-chamber view in the atrial switch group showed a significant negative correlation with the RV Tei index (r = -0.58, p < 0.01). The RV Tei index increased with increasing severity of the NYHA functional class. In the moderate/severe tricuspid regurgitation group, it was significantly higher than in patients with none/trivial tricuspid regurgitation. We conclude that the RV Tei index is useful for evaluating RV junction long after the atrial switch operation for d-TGA.
右心室(RV)功能障碍可能发生在大动脉d型转位(d-TGA)心房调转术后的患者中,并且可能是一种重要的并发症。对于这些患者的随访,使用超声心动图对右心室功能进行无创评估是必要的。我们使用多普勒Tei指数(右心室Tei指数)评估右心室功能。右心室Tei指数测量等容收缩和舒张的总时间间隔与射血时间的比值。研究对象包括33例接受d-TGA心房调转术的患者(心房调转组)(平均年龄21±4岁)、10例接受d-TGA动脉调转术后合并肺动脉狭窄的患者(动脉调转组)(平均年龄17±1岁)以及10例心脏结构正常的患者作为对照组(平均年龄26±7岁)。心房调转组的右心室Tei指数(0.65±0.16)显著高于动脉调转组(0.29±0.07)和对照组(0.29±0.01)(p<0.05)。心房调转组四腔心切面获得的右心室面积变化分数与右心室Tei指数呈显著负相关(r=-0.58,p<0.01)。右心室Tei指数随纽约心脏协会(NYHA)功能分级严重程度的增加而升高。在中/重度三尖瓣反流组中,该指数显著高于无/轻度三尖瓣反流的患者。我们得出结论,右心室Tei指数对于评估d-TGA心房调转术后很长一段时间的右心室功能是有用的。