Yi Hyeong-Joong, Kim Kwang-Myung, Ko Yong, Kim Young-Soo, Oh Suck-Jun, Oh Seong-Hoon
Department of Neurosurgery, Hanyang University Medical Center, Sungdong-gu, 133-792 Seoul, South Korea.
Childs Nerv Syst. 2006 Jan;22(1):8-12. doi: 10.1007/s00381-005-1214-5. Epub 2005 Aug 31.
Intracranial pseudoaneurysms, infrequent vascular lesion in children and adolescents, are characterized by the presence of organizing hematoma and fibrosis outside the true lumen instead of normal vascular elements. Because most pseudoaneurysms result from eminent insults such as major trauma or grave infection, development without preceding incident is extremely rare. Giant pseudoaneurysms in younger population, albeit unexceptionally unusual, are symptomatic in most instances and exhibit very high risk of rupture. Clinical manifestation as chronic headache without hemorrhage or neural compression is very unlikely. Once identified, only prompt surgical treatment guarantees favorable prognosis.
We report a case of a 17-year-old boy with a giant pseudoaneurysm arising at distal middle cerebral artery. He complained of headache that had become apparent 3 years ago and medically intractable 3 months ago. Brain computed tomographic scan and lumbar cerebrospinal spinal fluid study revealed no trace of recent hemorrhage. However, digital subtraction angiography revealed a huge aneurysmal dilatation along the right distal middle cerebral artery with the features of delayed filling and emptying of contrast agent. Surgical obliteration of the corresponding aneurysm with tandem clipping and aneurysmectomy made him free of headache postoperatively.
We could not uncover the actual cause of formation and precise mechanism of clinical presentation for this unique aneurysm; nevertheless, we suggest that blunt head injury of fairly long history caused such a lesion, and repeated minute bleeding elicited headache. This assumption was possible only after full consideration of the histopathology.
颅内假性动脉瘤在儿童和青少年中是一种罕见的血管病变,其特征是在真腔外存在机化血肿和纤维化,而非正常血管成分。由于大多数假性动脉瘤是由重大创伤或严重感染等明显损伤引起的,无前兆事件而发生的情况极为罕见。年轻人群中的巨大假性动脉瘤虽然极其罕见,但在大多数情况下有症状,且破裂风险非常高。临床表现为无出血或神经受压的慢性头痛的情况极不可能。一旦确诊,只有及时手术治疗才能保证良好预后。
我们报告一例17岁男孩,其大脑中动脉远端出现巨大假性动脉瘤。他主诉头痛,3年前开始出现,3个月前药物治疗无效。脑部计算机断层扫描和腰椎脑脊液检查未发现近期出血迹象。然而,数字减影血管造影显示右侧大脑中动脉远端有巨大动脉瘤样扩张,造影剂有延迟充盈和排空特征。通过串联夹闭和动脉瘤切除术对相应动脉瘤进行手术闭塞,术后他不再头痛。
我们无法揭示这种独特动脉瘤形成的实际原因和临床表现的确切机制;尽管如此,我们认为相当长时间的钝性头部损伤导致了这种病变,反复的微量出血引发了头痛。只有在充分考虑组织病理学后,这种假设才有可能成立。