March Philip A, Muir William W
Department of Veterinary Clinical Sciences, College of Veterinary Medicine, The Ohio State University, Columbus, OH, USA.
Vet Anaesth Analg. 2005 Sep;32(5):241-55. doi: 10.1111/j.1467-2995.2005.00221.x.
To evaluate the different methodologies used to monitor anesthetic depth and to review the principles and potential applications of bispectral index (BIS) monitoring in veterinary anesthesia.
Medline (1966 to present); Pubmed (mid-1960s to present); personal files.
Current anesthetic monitoring techniques rely on indirect measures of corticocerebral arousal after a noxious stimulus. Some anesthetics and pre-anesthetics suppress responses that are used to gauge adequate hypnosis and analgesia. The BIS is a direct measure of corticocerebral activation and is inversely related to the degree of hypnosis. Dynamic changes in the BIS after a noxious stimulus may signify early nociceptive activation of the cerebral cortex and may be a useful marker of inadequate analgesia. However, application of this technique during the use of various drug combinations (i.e. clinical anesthesia) will require further research and understanding.
评估用于监测麻醉深度的不同方法，并综述脑电双频指数（BIS）监测在兽医麻醉中的原理及潜在应用。
医学索引数据库（1966年至今）；医学期刊数据库（20世纪60年代中期至今）；个人文档。
当前的麻醉监测技术依赖于对有害刺激后大脑皮质觉醒的间接测量。一些麻醉药和麻醉前用药会抑制用于评估充分催眠和镇痛的反应。BIS是大脑皮质激活的直接测量指标，与催眠程度呈负相关。有害刺激后BIS的动态变化可能表明大脑皮质早期伤害性激活，可能是镇痛不足的有用指标。然而，在使用各种药物组合（即临床麻醉）期间应用该技术将需要进一步的研究和理解。
