Zoltick Barbara H, Jacobs Linda A, Vaughn David J
Division of Hematology Oncology, University of Pennsylvania Hospital, Philadelphia, PA, USA.
Oncol Nurs Forum. 2005 Sep 1;32(5):1005-9; quiz 1010-1. doi: 10.1188/05.ONF.1005-1012.
PURPOSE/OBJECTIVES: To explore what is known regarding cardiovascular late effects of treatment, such as Raynaud phenomenon, hypertension, hyperlipidemia, and coronary artery disease as well as the risk for cardiovascular events experienced by patients with testicular cancer treated with chemotherapy.
Literature review of treatment options and cardiovascular risk in patients with testicular cancer from PubMed, MEDLINE, oncology nursing literature, and the Internet.
Evidence exists that chemotherapy used to treat testicular cancer may increase risk of cardiovascular disease. More research is needed to clarify the risks further. Patients and their healthcare providers must be aware of the potential toxicities.
A limited but growing body of research is focused on defining cardiovascular risks in this population.
Nurses have an important role in exploring and identifying cardiovascular risk factors in patients, furthering research to clarify the risks, and using the knowledge to improve patient care and education.
目的/目标：探讨关于治疗的心血管远期效应，如雷诺现象、高血压、高脂血症和冠状动脉疾病，以及接受化疗的睾丸癌患者发生心血管事件的风险。
来自PubMed、MEDLINE、肿瘤护理文献和互联网的关于睾丸癌患者治疗选择和心血管风险的文献综述。
有证据表明，用于治疗睾丸癌的化疗可能会增加心血管疾病的风险。需要更多研究来进一步明确风险。患者及其医疗保健提供者必须意识到潜在的毒性。
针对确定该人群心血管风险的研究数量有限，但在不断增加。
护士在探索和识别患者心血管危险因素、推动研究以明确风险以及利用这些知识改善患者护理和教育方面发挥着重要作用。
