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[动脉硬化闭塞症患者术前进行血液灌流和降血脂治疗后脂质代谢的变化]

[Changes in lipid metabolism in patients with arteriosclerosis obliterans after charcoal hemoperfusion and hypolipidemic therapy in the preoperative period].

作者信息

Burlakov S G, Diuzhikov A A, Beliavskiĭ V I, Golenko L A, Domnikova A A

出版信息

Kardiologiia. 1992 Jan;32(1):18-21.

PMID:1614014
Abstract

The paper analyzes the results of the treatment of 26 patients with atherosclerosis obliterans of the lower extremities, which has been performed to make an intensive hypolipidemic preparation for an operation. The comprehensive approach based on the combination of medication (nicotinic acid, and its derivatives, cholestyramine, and SKH -2K charcoal hemoperfusion ) and efferent therapy reduced the plasma levels of total cholesterol by 27%, triglycerides to 48%, low density lipoprotein cholesterol to 40%, and increased high density lipoprotein cholesterol up to 72%. The similar course therapy may be repeatedly used in a follow-up of this group of patients.

摘要

本文分析了26例下肢动脉硬化闭塞症患者的治疗结果,这些治疗是为手术进行强化降血脂准备。基于药物(烟酸及其衍生物、消胆胺和SKH -2K活性炭血液灌注)与传出疗法相结合的综合方法,使总胆固醇血浆水平降低了27%,甘油三酯降低至48%,低密度脂蛋白胆固醇降低至40%,高密度脂蛋白胆固醇升高至72%。这种类似的疗程疗法可在该组患者的随访中重复使用。

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