Menzi J, Körner F
Universitäts-Augenklinik Bern.
Klin Monbl Augenheilkd. 1992 May;200(5):349-53. doi: 10.1055/s-2008-1045763.
A non-arteritic anterior ischemic optic neuropathy has usually a poor prognosis. Spontaneous remissions are extremely rare. In contrast to arteritic anterior ischemic neuropathy, systemic corticosteroids are generally accepted to be ineffective. Two cases of bilateral severe non-arteritic anterior ischemic optic neuropathy are reported who underwent full remission of their visual function directly related to high-dose systemic corticosteroids. It is hypothesized that, in acute phases of non-arteritic anterior ischemic optic neuropathy a significant reduction of tissue swelling and consecutive prelaminar reperfusion can be achieved with high-dose corticosteroids.
非动脉炎性前部缺血性视神经病变通常预后较差。自发缓解极为罕见。与动脉炎性前部缺血性神经病变不同，全身使用皮质类固醇一般被认为无效。本文报告了两例双侧严重非动脉炎性前部缺血性视神经病变患者，他们的视功能因大剂量全身皮质类固醇治疗而完全缓解。据推测，在非动脉炎性前部缺血性视神经病变的急性期，大剂量皮质类固醇可显著减轻组织肿胀并实现连续的层前再灌注。
