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[非动脉炎性前部缺血性视神经病变的全身糖皮质激素治疗]

[Systemic corticosteroid therapy in non-arteritic anterior ischemic optic neuropathy].

作者信息

Menzi J, Körner F

机构信息

Universitäts-Augenklinik Bern.

出版信息

Klin Monbl Augenheilkd. 1992 May;200(5):349-53. doi: 10.1055/s-2008-1045763.

Abstract

A non-arteritic anterior ischemic optic neuropathy has usually a poor prognosis. Spontaneous remissions are extremely rare. In contrast to arteritic anterior ischemic neuropathy, systemic corticosteroids are generally accepted to be ineffective. Two cases of bilateral severe non-arteritic anterior ischemic optic neuropathy are reported who underwent full remission of their visual function directly related to high-dose systemic corticosteroids. It is hypothesized that, in acute phases of non-arteritic anterior ischemic optic neuropathy a significant reduction of tissue swelling and consecutive prelaminar reperfusion can be achieved with high-dose corticosteroids.

摘要

非动脉炎性前部缺血性视神经病变通常预后较差。自发缓解极为罕见。与动脉炎性前部缺血性神经病变不同,全身使用皮质类固醇一般被认为无效。本文报告了两例双侧严重非动脉炎性前部缺血性视神经病变患者,他们的视功能因大剂量全身皮质类固醇治疗而完全缓解。据推测,在非动脉炎性前部缺血性视神经病变的急性期,大剂量皮质类固醇可显著减轻组织肿胀并实现连续的层前再灌注。

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