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[支气管肺泡灌洗在间质性肺疾病管理中的作用]

[Contribution of bronchoalveolar lavage to the management of interstitial lung disease].

作者信息

Israel-Biet Dominique, Danel Claire

机构信息

Service de Pneumologie, Hôpital Européen Georges-Pompidou, 20, rue Leblanc, 75015 Paris, Faculté de Médecine Paris-5.

出版信息

Rev Pneumol Clin. 2005 Jun;61(3):141-8. doi: 10.1016/s0761-8417(05)84805-9.

Abstract

Bronchoalveolar lavage (BAL) is a minimally invasive method for exploring the distal lung. It enables collection of free cellular and acellular material present in the alveoli. Over the last two decades BAL has become a fundamental tool for positive diagnosis of interstitial lung disease and even more for differential diagnosis. It has contributed greatly to the diagnosis of lung infections, particularly in immunosuppressed patients. In the context of non-infectious infiltrative disease, the diagnostic contribution of BAL is limited due to the lack of a specific cell profile. It remains a fundamental tool for the differential diagnosis of idiopathic interstitial pneumonia. With BAL, a number of infectious or tumoral diseases can be ruled out with precision. It is also an important element for the evaluation of possible iatrogenic disease. BAL has transformed the diagnosis of interstitial lung disease and considerably reduced the indications for surgical biopsy.

摘要

支气管肺泡灌洗(BAL)是一种用于探查肺远端的微创方法。它能够收集肺泡中存在的游离细胞和无细胞物质。在过去二十年中,BAL已成为间质性肺疾病阳性诊断的基本工具,在鉴别诊断方面更是如此。它对肺部感染的诊断有很大帮助,尤其是在免疫抑制患者中。在非感染性浸润性疾病的背景下,由于缺乏特定的细胞特征,BAL的诊断作用有限。它仍然是特发性间质性肺炎鉴别诊断的基本工具。通过BAL,可以精确排除多种感染性或肿瘤性疾病。它也是评估可能的医源性疾病的重要因素。BAL改变了间质性肺疾病的诊断方式,并大大减少了手术活检的指征。

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