[疑似坏死性小肠结肠炎早产儿呼出气中氢气的测定]
[Determination of hydrogen in expiratory air of premature infants in suspected necrotizing enterocolitis].
作者信息
Rauter L, Startinig B, Mutz I
机构信息
Kinderabteilung des Landeskrankenhauses Leoben, Osterreich.
出版信息
Monatsschr Kinderheilkd. 1992 May;140(5):296-9.
BACKGROUND
Breath hydrogen (H2) analysis has been recommended for the differential diagnosis between necrotizing enterocolitis and transient feeding intolerance.
METHODS
We performed 360 breath H2 analyses in 32 unselected premature babies by use of an electrochemical method.
RESULTS
All babies on oral feedings excreted H2. The concentration of H2 in expired air was extremely variable and often high even in well premature babies. Antibiotic medication (other than penicillin G alone) inhibited breath hydrogen excretion.
CONCLUSIONS
Breath hydrogen analysis can be used as a diagnostic tool for necrotizing enterocolitis if performed in a symptomatic child on oral feedings prior to the initiation of antibiotic therapy.
背景
呼气氢（H2）分析已被推荐用于坏死性小肠结肠炎与短暂性喂养不耐受的鉴别诊断。
方法
我们采用电化学方法对32例未经挑选的早产儿进行了360次呼气H2分析。
结果
所有经口喂养的婴儿均呼出H2。即使是健康的早产儿，呼出气体中H2的浓度也极具变化且常常很高。使用抗生素（除单独使用青霉素G外）会抑制呼气氢的排出。
结论
如果在有症状且正在经口喂养的儿童开始抗生素治疗之前进行呼气氢分析，其可作为坏死性小肠结肠炎的诊断工具。
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