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Detection of fungemia by polymerase chain reaction in critically ill neonates and children.
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Late-onset sepsis in very low birth weight neonates: the experience of the NICHD Neonatal Research Network.极低出生体重儿晚发性败血症：美国国立儿童健康与人类发展研究所新生儿研究网络的经验
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Epidemiological, clinical, and microbiological characteristics of late-onset sepsis among very low birth weight infants in Israel: a national survey.以色列极低出生体重儿晚发性败血症的流行病学、临床和微生物学特征：一项全国性调查。
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Detection of bacterial DNA by PCR and reverse hybridization in the 16S rRNA gene with particular reference to neonatal septicemia.通过聚合酶链反应（PCR）和16S核糖体RNA（rRNA）基因的反向杂交检测细菌DNA，特别涉及新生儿败血症。
Acta Paediatr. 2001 Feb;90(2):179-83. doi: 10.1080/080352501300049389.
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Fulminant late-onset sepsis in a neonatal intensive care unit, 1988-1997, and the impact of avoiding empiric vancomycin therapy.1988 - 1997年新生儿重症监护病房暴发性迟发性败血症以及避免经验性万古霉素治疗的影响
Pediatrics. 2000 Dec;106(6):1387-90. doi: 10.1542/peds.106.6.1387.
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Rapid extraction from and direct identification in clinical samples of methicillin-resistant staphylococci using the PCR.使用聚合酶链反应（PCR）从临床样本中快速提取并直接鉴定耐甲氧西林葡萄球菌
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Frequency of low-level bacteremia in children from birth to fifteen years of age.从出生到15岁儿童的低水平菌血症发生率
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Late-onset sepsis in very low birth weight neonates: a report from the National Institute of Child Health and Human Development Neonatal Research Network.极低出生体重新生儿迟发性败血症：美国国立儿童健康与人类发展研究所新生儿研究网络的报告
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基于聚合酶链反应的新生儿葡萄球菌血症诊断

PCR-based diagnosis of neonatal staphylococcal bacteremias.

作者信息

Makhoul Imad R, Smolkin Tatiana, Sujov Polo, Kassis Imad, Tamir Ada, Shalginov Raia, Sprecher Hannah

机构信息

Department of Microbiology, Rambam Medical Center, Bat-Galim, Haifa, Israel.

出版信息

J Clin Microbiol. 2005 Sep;43(9):4823-5. doi: 10.1128/JCM.43.9.4823-4825.2005.

DOI:10.1128/JCM.43.9.4823-4825.2005
PMID:16145149
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC1234095/
Abstract

We compared PCR with blood cultures in the diagnosis of neonatal staphylococcal sepsis. Significant association was observed between PCR-based and culture-based diagnosis of staphylococcal bacteremia. Positive and negative predictive values for PCR were 100% and 98%, respectively. These data indicate that PCR may serve as a useful adjunct for the rapid diagnosis of staphylococcal sepsis.

摘要

我们比较了聚合酶链反应（PCR）与血培养在新生儿葡萄球菌败血症诊断中的作用。基于PCR和基于培养的葡萄球菌菌血症诊断之间存在显著关联。PCR的阳性预测值和阴性预测值分别为100%和98%。这些数据表明，PCR可作为快速诊断葡萄球菌败血症的有用辅助手段。