Pernkopf Dominik, Plas Eugen, Lang Thomas, Daha Kurosch, Kubin Klaus, Treu Thomas, Pflüger Heinz
Department of Urology and Ludwig Boltzmann Institute for Urology and Andrology, Lainz Hospital Vienna, Austria.
J Urol. 2005 Oct;174(4 Pt 1):1436-9; discussion 1439. doi: 10.1097/01.ju.0000173694.86127.ae.
Uroflowmetry is well established for investigating lower urinary tract symptoms. Current nomograms are based on sample sizes limited to 8 men of the same age. We generated percentile curves for the maximum urinary flow rate (Qmax) in relation to voided volume in male adolescents in a large homogenous healthy group.
A total of 348 males who were 18 years old were investigated, excluding probands with a urological history. Only samples with a voided volume of 150 cc or more were included. One micturition was obtained per proband to determine Qmax, the average urinary flow rate, time to Qmax and volume. Resulting curves were compared with nomograms for children and adults.
Average voided volume +/- SD was 262 +/- 91.9 cc (range 151 to 664). Qmax was 28.4 +/- 9.7 cc per second (range 11.4 to 76) with an average urinary flow rate of 18.6 +/- 5.5 cc per second (range 4 to 44), a micturition time of 16.9 +/- 6.8 seconds (range 7 to 48) and a mean time to Qmax of 7.8 +/- 4.1 seconds (range 1 to 25). A total of 341 probands had a Qmax of more than 15 cc per second, while only 7 showed a Qmax of less than 15 cc per second. At up to 350 cc Qmax increased with volume, followed by a plateau phase at 350 to 550 cc and a Qmax decrease at higher volumes.
Voiding volumes in a large homogenous adolescent group demonstrated optimal Qmax at voiding volumes between 350 and 550 cc with a decrease at higher volumes. Therefore, uroflow studies in adolescent males should be interpreted with caution at volumes less than 350 and more than 550 cc.
尿流率测定在调查下尿路症状方面已得到广泛应用。目前的列线图所基于的样本量仅限于8名同一年龄段的男性。我们在一个大型同质健康群体中生成了男性青少年最大尿流率（Qmax）与排尿量相关的百分位数曲线。
共对348名18岁男性进行了调查，排除有泌尿系统病史的先证者。仅纳入排尿量为150 cc或更多的样本。每位先证者获取一次排尿情况以确定Qmax、平均尿流率、达到Qmax的时间和尿量。将所得曲线与儿童和成人的列线图进行比较。
平均排尿量±标准差为262±91.9 cc（范围151至664）。Qmax为每秒28.4±9.7 cc（范围11.4至76），平均尿流率为每秒18.6±5.5 cc（范围4至44），排尿时间为16.9±6.8秒（范围7至48），达到Qmax的平均时间为7.8±4.1秒（范围1至25）。共有341名先证者的Qmax超过每秒15 cc，而只有7名先证者的Qmax低于每秒15 cc。在排尿量达到350 cc之前，Qmax随尿量增加，随后在350至550 cc出现平台期，尿量更高时Qmax下降。
在一个大型同质青少年群体中，排尿量在350至550 cc之间时Qmax最佳，尿量更高时Qmax下降。因此，对于青少年男性的尿流研究，在尿量小于350 cc和大于550 cc时应谨慎解读。
