Sharma M, Sinha R, Hussey K, Fouyas I P
Department of Histopathology, Aberdeen Royal Infirmary, Aberdeen, Scotland.
Neurosurgery. 2005 Sep;57(3):E596; discussion E596. doi: 10.1227/01.neu.0000170987.14821.6f.
Tumoral calcinosis is a rare disorder presenting with tumor-like masses of calcification, usually in soft tissues around large joints. Although this condition has been reported in the spine, this is the first reported instance of this uncommon lesion occurring in the intradural compartment, involving the filum terminale.
A 55-year-old man presented with back and right leg pain. Initial investigations revealed no cause. A review of his original magnetic resonance imaging scans revealed an intradural calcified mass at L3 level. Surgical exploration was undertaken.
A L3 laminectomy revealed a calcified mass adherent to the filum terminale. Frozen section from this mass revealed tumoral calcinosis involving the filum terminale.
This is the first known case of intradural involvement by tumoral calcinosis. This is an uncommon disorder, and a high index of suspicion is required to diagnose the condition, which can recur if incompletely removed.
肿瘤性钙化是一种罕见的疾病,表现为肿瘤样钙化团块,通常位于大关节周围的软组织中。虽然这种情况在脊柱中已有报道,但这是首次报道这种罕见病变发生在硬膜内腔,累及终丝。
一名55岁男性出现背部和右腿疼痛。初步检查未发现病因。对其原始磁共振成像扫描的复查显示L3水平有一个硬膜内钙化肿块。进行了手术探查。
L3椎板切除术显示一个钙化肿块附着于终丝。该肿块的冰冻切片显示肿瘤性钙化累及终丝。
这是已知的首例肿瘤性钙化累及硬膜内的病例。这是一种罕见的疾病,诊断时需要高度怀疑,若切除不完全可能复发。