• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

颈椎肿瘤性钙化症:一例报告并文献复习

Tumoral calcinosis in the cervical spine: a case report and review of the literature.

作者信息

Guo Rui, Kurata Tatsuya, Kondo Tetsushi, Imanishi Takao, Mizuno Tetsutaro, Sakakibara Toshihiko, Kasai Yuichi

机构信息

Department of Spinal Surgery and Medical Engineering, Mie University Graduate School of Medicine, 2-174 Edobashi, Tsu City, Mie, 514-8507, Japan.

Department of Orthopaedics, The Third People's Hospital of Kunshan, Kunshan, Jiangsu, China.

出版信息

J Med Case Rep. 2017 Oct 27;11(1):304. doi: 10.1186/s13256-017-1474-1.

DOI:10.1186/s13256-017-1474-1
PMID:29073937
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5658931/
Abstract

BACKGROUND

Tumoral calcinosis is rarely located in spine. A 55-year-old Japanese woman with cervical tumoral calcinosis is presented, along with a review of the literature relating to tumoral calcinosis in the spine. We discussed the etiology, diagnosis, and management of this condition.

CASE PRESENTATION

We report a case of a patient with cervical tumoral calcinosis with end-stage renal disease. A computed tomography scan showed a lobulated, calcified mass around the right facet joint at the fourth-fifth cervical spine and calcifications were also observed in the right intervertebral foramens at fourth-fifth cervical spine and fifth-sixth cervical spine levels and the anterior wall of the spinal canal. By performing a cervical decompression and stabilization, the patient recovered from her neurological symptoms.

CONCLUSIONS

Although tumoral calcinosis is rarely located in the spine, it should be considered in the differential diagnosis of spinal lesions. If a calcified mass causes acute neurological symptoms, resection of the mass is still the most important treatment.

摘要

背景

肿瘤性钙化很少发生于脊柱。本文报道了一名55岁患有颈椎肿瘤性钙化的日本女性病例,并对脊柱肿瘤性钙化的相关文献进行了综述。我们讨论了该疾病的病因、诊断及治疗。

病例介绍

我们报告了一例患有颈椎肿瘤性钙化且伴有终末期肾病的患者。计算机断层扫描显示,在颈椎4-5水平右侧小关节周围有一个分叶状钙化肿块,同时在颈椎4-5及5-6水平的右侧椎间孔和椎管前壁也观察到钙化。通过进行颈椎减压和固定手术,患者的神经症状得以恢复。

结论

尽管肿瘤性钙化很少发生于脊柱,但在脊柱病变的鉴别诊断中应予以考虑。如果钙化肿块引起急性神经症状,切除肿块仍是最重要的治疗方法。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/cfe4/5658931/7b95f2ae9f74/13256_2017_1474_Fig4_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/cfe4/5658931/b4e770f22edb/13256_2017_1474_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/cfe4/5658931/3680c96591b9/13256_2017_1474_Fig2_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/cfe4/5658931/76e368bf630a/13256_2017_1474_Fig3_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/cfe4/5658931/7b95f2ae9f74/13256_2017_1474_Fig4_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/cfe4/5658931/b4e770f22edb/13256_2017_1474_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/cfe4/5658931/3680c96591b9/13256_2017_1474_Fig2_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/cfe4/5658931/76e368bf630a/13256_2017_1474_Fig3_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/cfe4/5658931/7b95f2ae9f74/13256_2017_1474_Fig4_HTML.jpg

相似文献

1
Tumoral calcinosis in the cervical spine: a case report and review of the literature.颈椎肿瘤性钙化症:一例报告并文献复习
J Med Case Rep. 2017 Oct 27;11(1):304. doi: 10.1186/s13256-017-1474-1.
2
Tumoral calcinosis of the cervical spine in a dialysis patient. Case report and review of the literature.一名透析患者颈椎的肿瘤性钙化症。病例报告及文献综述。
Neurol Neurochir Pol. 2017 Mar-Apr;51(2):163-169. doi: 10.1016/j.pjnns.2016.12.001. Epub 2016 Dec 14.
3
Uremic tumoral calcinosis in the cervical spine: case report.颈椎尿毒症性肿瘤性钙化:病例报告
J Neurosurg Spine. 2016 Jul;25(1):26-30. doi: 10.3171/2015.12.SPINE151085. Epub 2016 Mar 4.
4
Unusual spinal manifestation in secondary hyperparathyroidism: a case report.继发性甲状旁腺功能亢进症的不寻常脊柱表现:一例报告
Spine (Phila Pa 1976). 2007 Sep 1;32(19):E557-60. doi: 10.1097/BRS.0b013e3181453f85.
5
Progressive myelopathy due to idiopathic intraspinal tumoral calcinosis of the cervical spine. Case report.颈椎特发性椎管内肿瘤性钙化所致进行性脊髓病。病例报告。
J Neurosurg Spine. 2007 Sep;7(3):362-5. doi: 10.3171/SPI-07/09/362.
6
Tumoral calcinosis of the craniovertebral junction as a cause of dysphagia with treatment by transoral decompression: case report.颅颈交界区肿瘤性钙化症致吞咽困难并经口减压治疗:病例报告
J Neurosurg Spine. 2017 May;26(5):567-571. doi: 10.3171/2016.9.SPINE16469. Epub 2017 Feb 10.
7
Tumoral calcinosis in bilateral facet joints of the lumbar spine in scleroderma. Case report.硬皮病患者腰椎双侧小关节肿瘤性钙质沉着症。病例报告。
J Neurosurg Spine. 2006 Nov;5(5):451-4. doi: 10.3171/spi.2006.5.5.451.
8
Tumoral calcinosis presenting as neck pain and mass lesion of the cervical spine.表现为颈部疼痛和颈椎肿块病变的肿瘤性钙化症。
Am J Orthop (Belle Mead NJ). 2008 Nov;37(11):E191-5.
9
Tumoral calcinosis of the lumbar and cervical spine.腰椎和颈椎的肿瘤性钙化症。
J Clin Neurosci. 2019 Apr;62:243-245. doi: 10.1016/j.jocn.2018.12.015. Epub 2019 Jan 3.
10
Tumoral calcinosis of the spine in the course of systemic sclerosis: report of a new case and review of the literature.系统性硬化症病程中脊柱肿瘤性钙质沉着症:一例新病例报告及文献复习
Clin Exp Rheumatol. 2015 Jul-Aug;33(4 Suppl 91):S175-8. Epub 2015 Aug 5.

引用本文的文献

1
Tumoral Calcinosis of the Thoracolumbar Spine Associated With Adjacent Segment Degeneration After Lumber Fusion: A Case of Myelopathy.腰椎融合术后胸腰椎肿瘤性钙化伴相邻节段退变:1例脊髓病病例
Cureus. 2025 Feb 28;17(2):e79851. doi: 10.7759/cureus.79851. eCollection 2025 Feb.
2
An Unusual Case of Uremic Tumoral Calcinosis with Atypical Manifestation in a Patient on Peritoneal Dialysis: Case Report and Review of the Literature.腹膜透析患者中表现不典型的尿毒症性肿瘤性钙化罕见病例:病例报告及文献复习
Med Sci (Basel). 2025 Jan 29;13(1):11. doi: 10.3390/medsci13010011.
3
Navigation-assisted resection of tumoral calcinosis of the lumbosacral spine: illustrative case.

本文引用的文献

1
Uremic tumoral calcinosis in the cervical spine: case report.颈椎尿毒症性肿瘤性钙化:病例报告
J Neurosurg Spine. 2016 Jul;25(1):26-30. doi: 10.3171/2015.12.SPINE151085. Epub 2016 Mar 4.
2
Tumoral calcinosis involving the cervical spine.累及颈椎的肿瘤性钙化症。
Surg Neurol Int. 2015 Jun 18;6:109. doi: 10.4103/2152-7806.159074. eCollection 2015.
3
Severe vascular calcification and tumoral calcinosis in a family with hyperphosphatemia: a fibroblast growth factor 23 mutation identified by exome sequencing.高磷血症家族中的严重血管钙化和肿瘤性钙化:通过外显子组测序鉴定出的成纤维细胞生长因子23突变
导航辅助下腰骶椎肿瘤性钙化切除术:病例展示
J Neurosurg Case Lessons. 2022 Jul 25;4(4):CASE22213. doi: 10.3171/CASE22213.
4
Symptomatic Cervical Tumoral Calcinosis due to Cosmetic Body Contouring Mineral Oil Injections.因美容美体轮廓塑造矿物油注射导致的有症状的颈椎肿瘤性钙化症。
Cureus. 2020 Nov 28;12(11):e11743. doi: 10.7759/cureus.11743.
5
Tumoral Calcinosis of Thoracic Spine Associated with Vertebral Fracture and Inflammatory Reactions.胸椎肿瘤性钙化伴椎体骨折及炎症反应
Case Rep Orthop. 2020 Jul 24;2020:8881698. doi: 10.1155/2020/8881698. eCollection 2020.
6
Infantile Tumoral Calcinosis of the Cervical Spine: A Case Report.颈椎婴儿期肿瘤性钙化症:一例报告
J Am Acad Orthop Surg Glob Res Rev. 2019 Mar 26;3(4):e062. doi: 10.5435/JAAOSGlobal-D-18-00062. eCollection 2019 Apr.
Nephrol Dial Transplant. 2014 Dec;29(12):2235-43. doi: 10.1093/ndt/gfu324. Epub 2014 Nov 5.
4
Long-term clinical outcome and phenotypic variability in hyperphosphatemic familial tumoral calcinosis and hyperphosphatemic hyperostosis syndrome caused by a novel GALNT3 mutation; case report and review of the literature.由新型GALNT3突变引起的高磷血症性家族性肿瘤性钙化症和高磷血症性骨肥厚综合征的长期临床结局及表型变异性;病例报告及文献复习
BMC Genet. 2014 Sep 24;15:98. doi: 10.1186/s12863-014-0098-3.
5
Cervical spine instability from tumoral calcinosis.肿瘤性钙化导致的颈椎不稳。
Acta Neurochir (Wien). 2013 Jul;155(7):1245-6. doi: 10.1007/s00701-013-1709-x. Epub 2013 Apr 21.
6
Isolated cervical spine facet joint tumoral calcinosis.孤立性颈椎小关节肿瘤性钙化症。
Spine J. 2013 Feb;13(2):208-9. doi: 10.1016/j.spinee.2012.11.029. Epub 2012 Dec 21.
7
Cervical tumoral calcinosis with secondary hyperparathyroidism in a chronic hemodialysis patient.一名慢性血液透析患者出现伴有继发性甲状旁腺功能亢进的颈椎肿瘤性钙化。
Hemodial Int. 2013 Jul;17(3):458-62. doi: 10.1111/j.1542-4758.2012.00760.x. Epub 2012 Oct 16.
8
Uremic tumoral calcinosis causing atlantoaxial subluxation and spinal cord compression in a patient on continuous ambulatory peritoneal dialysis.血液透析患者发生持续性不卧床腹膜透析致尿毒症性肿瘤性钙化引起寰枢椎半脱位和脊髓压迫
Int Urol Nephrol. 2013 Oct;45(5):1511-6. doi: 10.1007/s11255-012-0215-z. Epub 2012 Jun 21.
9
Uremic tumoral calcinosis in patients on peritoneal dialysis: clinical, radiologic, and laboratory features.尿毒症性肿瘤样钙质沉着症在腹膜透析患者中的临床、放射学和实验室特征。
Perit Dial Int. 2011 Jul-Aug;31(4):430-9. doi: 10.3747/pdi.2009.00250. Epub 2011 Feb 28.
10
Tumoral calcinosis and epidural lipomatosis of the lumbar spine.肿瘤性钙化症与腰椎硬膜外脂肪增多症。
Turk Neurosurg. 2011 Jan;21(1):110-2.