Taweevisit Mana, Thanakit Voranuch
Department of Pathology, Faculty of Medicine, Chulalongkorn University, Bangkok, Thailand.
J Med Assoc Thai. 2005 Apr;88(4):538-40.
Myxoid liposarcoma is a malignant soft tissue tumor with a relatively indolent natural history. It commonly occurs in the extremities with extrapulmonary metastatic potential. Round cell liposarcoma, recently, is widely agreed to be the aggressive counterpart of the myxoid liposarcoma, mostly arising in adverse, local recurrence, and metastatic lesions. Metastatic liposarcoma with pure myxoid element is unusual. The authors report an extremely rare case of a 47-year-old Thai male patient having a metastatic pure myxoid liposarcoma to the thoracic vertebrae, one year after primary tumor documented on the left thigh. Histology of the primary and metastatic sites shows only myxoid pattern. Round cell feature was not documented. To the best of the authors' knowledge, this is the second case report of metastatic myxoid liposarcoma without round cell morphology.
黏液样脂肪肉瘤是一种恶性软组织肿瘤，其自然病程相对惰性。它通常发生于四肢，具有肺外转移潜能。近来，圆形细胞脂肪肉瘤被广泛认为是黏液样脂肪肉瘤的侵袭性对应物，大多发生于不良的局部复发和转移病灶中。具有纯黏液样成分的转移性脂肪肉瘤并不常见。作者报告了一例极其罕见的病例，一名47岁的泰国男性患者，在左大腿原发性肿瘤确诊一年后，出现了胸椎转移性纯黏液样脂肪肉瘤。原发部位和转移部位的组织学检查仅显示黏液样模式。未记录到圆形细胞特征。据作者所知，这是第二例无圆形细胞形态的转移性黏液样脂肪肉瘤病例报告。
