Lee Won Ae
Department of Pathology, College of Medicine, Dankook University, Cheonan, Republic of Korea.
World J Surg Oncol. 2005 Sep 7;3:59. doi: 10.1186/1477-7819-3-59.
Mucinous cystic neoplasm (MCN) of the pancreas is basically cystic epithelial neoplasm, unilocular or multilocular, occurring almost exclusively in women.
A 51-year-old female presented with a pancreatic mass incidentally found on the abdominal computed tomography. She underwent distal pancreatectomy. The sectioned surface of the pancreas revealed a circumscribed, whitish gray ovoid firm mass with some cystic spaces. Microscopically, glandular or small cystic structures were scattered in the predominant stroma creating a solid appearance. The subepithelial stromal component was composed of cytologically bland looking spindle cells, which resembled ovarian stroma. The stromal cells were reactive to CD 34, vimentin, progesterone receptor and calretinin. The microscopy was consistent with mucinous cystadenoma of the pancreas.
This case of mucinous cystadenoma of the pancreas showed very interesting pathology: It was solid rather than cystic, and accompanied by abundant benign transitional epithelia, which was a very unusual and novel finding in the mucinous cystic neoplasm of the pancreas.
胰腺黏液性囊性肿瘤（MCN）基本上是一种囊性上皮性肿瘤，单房或多房，几乎仅发生于女性。
一名51岁女性因腹部计算机断层扫描偶然发现胰腺肿物。她接受了胰腺远端切除术。胰腺的切面显示有一个边界清楚、灰白色卵圆形坚实肿物，伴有一些囊腔。显微镜下，腺管或小囊状结构散在于主要的间质中，形成实性外观。上皮下间质成分由细胞学表现温和的梭形细胞组成，类似卵巢间质。间质细胞对CD 34、波形蛋白、孕激素受体和钙视网膜蛋白呈阳性反应。显微镜检查结果符合胰腺黏液性囊腺瘤。
该例胰腺黏液性囊腺瘤显示出非常有趣的病理学特征：它是实性而非囊性，并且伴有丰富的良性移行上皮，这在胰腺黏液性囊性肿瘤中是非常不寻常且新颖的发现。
