Wilson R S, Scherr P A, Bienias J L, Mendes de Leon C F, Everson-Rose S A, Bennett D A, Evans D A
Rush Alzheimer's Disease Center, Rush Institute for Healthy Aging and Department of Neurological Sciences, Rush University Medical Center, Chicago, IL 60612, USA.
Exp Aging Res. 2005 Oct-Dec;31(4):393-407. doi: 10.1080/03610730500206683.
We examined the relation of early life socioeconomic circumstances to cognition in older residents of a biracial urban community. Participants had brief cognitive testing three times at approximately 3-year intervals. At baseline, information about early life household and county socioeconomic level was collected. In mixed-effects models adjusted for age, sex, race, and education, both early life household and county socioeconomic levels were positively associated with baseline level of cognition but unrelated to cognitive decline. The results suggest that socioeconomic conditions in early life are associated with level of cognitive function in old age but not with rate of cognitive decline.
我们研究了一个混血城市社区老年居民早年的社会经济状况与认知能力之间的关系。参与者大约每隔3年接受三次简短的认知测试。在基线时，收集了有关早年家庭和所在县社会经济水平的信息。在对年龄、性别、种族和教育程度进行调整的混合效应模型中，早年家庭和所在县的社会经济水平均与认知基线水平呈正相关，但与认知衰退无关。结果表明，早年的社会经济状况与老年时的认知功能水平有关，但与认知衰退率无关。
