An Epac-dependent pain pathway.
作者信息
Griffin Robert S
机构信息
Harvard Medical School, Department of Anesthesia and Critical Care, Massachusetts General Hospital, Charlestown, Massachusetts 02129, USA.
出版信息
J Neurosci. 2005 Sep 7;25(36):8113-4. doi: 10.1523/JNEUROSCI.3044-05.2005.
Abstract
摘要
相似文献
1
An Epac-dependent pain pathway.
J Neurosci. 2005 Sep 7;25(36):8113-4. doi: 10.1523/JNEUROSCI.3044-05.2005.
2
Estrogen controls PKCepsilon-dependent mechanical hyperalgesia through direct action on nociceptive neurons.
Eur J Neurosci. 2006 Jul;24(2):527-34. doi: 10.1111/j.1460-9568.2006.04913.x. Epub 2006 Jul 12.
3
Ca++/CaMKII switches nociceptor-sensitizing stimuli into desensitizing stimuli.
J Neurochem. 2012 Nov;123(4):589-601. doi: 10.1111/j.1471-4159.2012.07920.x. Epub 2012 Sep 28.
4
A critical role of the cAMP sensor Epac in switching protein kinase signalling in prostaglandin E2-induced potentiation of P2X3 receptor currents in inflamed rats.
J Physiol. 2007 Oct 1;584(Pt 1):191-203. doi: 10.1113/jphysiol.2007.135616. Epub 2007 Aug 16.
5
Epac mediates a cAMP-to-PKC signaling in inflammatory pain: an isolectin B4(+) neuron-specific mechanism.
J Neurosci. 2005 Jun 29;25(26):6119-26. doi: 10.1523/JNEUROSCI.0285-05.2005.
6
Coupling of neuronal 5-HT7 receptors to activation of extracellular-regulated kinase through a protein kinase A-independent pathway that can utilize Epac.
J Neurochem. 2003 Dec;87(5):1076-85. doi: 10.1046/j.1471-4159.2003.02076.x.
7
Possible role of the exchange protein directly activated by cyclic AMP (Epac) in the cyclic AMP-dependent functional differentiation and syncytialization of human placental BeWo cells.
Hum Reprod. 2010 Sep;25(9):2229-38. doi: 10.1093/humrep/deq190. Epub 2010 Jul 27.
8
EXPRESS: F-actin links Epac-PKC signaling to purinergic P2X3 receptors sensitization in dorsal root ganglia following inflammation.
Mol Pain. 2016 Jul 5;12. doi: 10.1177/1744806916660557. Print 2016.
9
Cyclic adenosine 3',5'-monophosphate (cAMP)-dependent protein kinases, but not exchange proteins directly activated by cAMP (Epac), mediate thyrotropin/cAMP-dependent regulation of thyroid cells.
Endocrinology. 2007 Oct;148(10):4612-22. doi: 10.1210/en.2007-0540. Epub 2007 Jun 21.
10
Cyclic AMP induces integrin-mediated cell adhesion through Epac and Rap1 upon stimulation of the beta 2-adrenergic receptor.
J Cell Biol. 2003 Feb 17;160(4):487-93. doi: 10.1083/jcb.200209105. Epub 2003 Feb 10.
引用本文的文献
1
Sex Differences in Protein Kinase A Signaling of the Latent Postoperative Pain Sensitization That Is Masked by Kappa Opioid Receptors in the Spinal Cord.
J Neurosci. 2021 Nov 24;41(47):9827-9843. doi: 10.1523/JNEUROSCI.2622-20.2021. Epub 2021 Sep 16.
2
An NPY Y1 receptor antagonist unmasks latent sensitization and reveals the contribution of protein kinase A and Epac to chronic inflammatory pain.
Pain. 2019 Aug;160(8):1754-1765. doi: 10.1097/j.pain.0000000000001557.
3
Spinal serum-inducible and glucocorticoid-inducible kinase 1 mediates neuropathic pain via kalirin and downstream PSD-95-dependent NR2B phosphorylation in rats.
J Neurosci. 2013 Mar 20;33(12):5227-40. doi: 10.1523/JNEUROSCI.4452-12.2013.
本文引用的文献
1
Epac mediates a cAMP-to-PKC signaling in inflammatory pain: an isolectin B4(+) neuron-specific mechanism.
J Neurosci. 2005 Jun 29;25(26):6119-26. doi: 10.1523/JNEUROSCI.0285-05.2005.
2
Topographically distinct epidermal nociceptive circuits revealed by axonal tracers targeted to Mrgprd.
Neuron. 2005 Jan 6;45(1):17-25. doi: 10.1016/j.neuron.2004.12.015.
3
Epac: a new cAMP target and new avenues in cAMP research.
Nat Rev Mol Cell Biol. 2003 Sep;4(9):733-8. doi: 10.1038/nrm1197.
4
Neuronal plasticity: increasing the gain in pain.
Science. 2000 Jun 9;288(5472):1765-9. doi: 10.1126/science.288.5472.1765.
5
A novel nociceptor signaling pathway revealed in protein kinase C epsilon mutant mice.
Neuron. 1999 Sep;24(1):253-60. doi: 10.1016/s0896-6273(00)80837-5.
Zotero 插件