Chomel Bruno B, Boulouis Henri-Jean
Department of Population Health and Reproduction, School of Veterinary Medicine, University of California, Davis, California 95616, USA.
Bull Acad Natl Med. 2005 Mar;189(3):465-77; discussion 477-80.
Domestic animals and wildlife represent a large reservoir for bartonellae, at least eight species or subspecies of which have been reported to cause zoonotic infections. In addition, numerous orphan clinical syndromes are now being attributed to Bartonella henselae infection. Many mammalian species, including cats, dogs, rodents and ruminants are the main bartonellae reservoirs. Cats are the main reservoir for B. henselae. It appears that domestic dogs, at least in non tropical regions, are more likely to be accidental hosts than reservoirs, and constitute excellent sentinels for human infections. Bartonellae are vector-borne bacteria. The mode of B. henselae transmission by cat fleas is now better understood, but new potential vectors have recently been identified, including ticks and biting flies. This articles summarizes current knowledge of the etiology, new clinical features and epidemiological characteristics of these emerging zoonoses.
家畜和野生动物是巴尔通体的一个巨大宿主库,据报道其中至少有8个物种或亚种可引起人畜共患病感染。此外,现在许多不明原因的临床综合征都被认为与亨氏巴尔通体感染有关。包括猫、狗、啮齿动物和反刍动物在内的许多哺乳动物物种是主要的巴尔通体宿主。猫是亨氏巴尔通体的主要宿主。至少在非热带地区,家犬似乎更有可能是偶然宿主而非宿主库,并且是人类感染的良好哨兵。巴尔通体是媒介传播细菌。目前对猫蚤传播亨氏巴尔通体的方式有了更好的了解,但最近发现了新的潜在媒介,包括蜱和咬蝇。本文总结了这些新发人畜共患病的病因、新临床特征和流行病学特征的当前知识。