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巨大冠状动脉瘤的外科治疗

Surgical treatment of giant coronary artery aneurysm.

作者信息

Li Dianyuan, Wu Qingyu, Sun Lizhong, Song Yunhu, Wang Wei, Pan Shiwei, Luo Guohua, Liu Yongmin, Qi Zhitao, Tao Tianfu, Sun Jian-Zhong, Hu Shengshou

机构信息

Department of Cardiovascular Surgery, Cardiovascular Institute and Fuwai Hospital, Chinese Academy of Medical Science and Peking Union Medical College, Beijing, The People's Republic of China.

出版信息

J Thorac Cardiovasc Surg. 2005 Sep;130(3):817-21. doi: 10.1016/j.jtcvs.2005.04.004.

Abstract

OBJECTIVE

Giant coronary artery aneurysm is an extremely uncommon disease. Most previous reports have involved only single cases. This report describes 6 patients with giant coronary artery aneurysm, examines its causes, and aims to establish the optimal surgical strategies for this exceptional and rare pathology.

METHODS

From July 1996 to October 2004, a total of 30,268 patients underwent heart surgery at Fuwai Hospital in Beijing. Among these, 6 patients had giant coronary artery aneurysm diagnosed and underwent operation. Various surgical strategies were used for the operations of these 6 patients, such as coronary artery aneurysm resection, coronary artery reconstruction, and concomitant coronary bypass. Additional procedures, such as fistula closure, aortic valve replacement, aortoplasty, and embolectomy, were done at same time for the patients with complications of coronary fistula, aortic valve insufficiency, or thrombus. Patients were followed up from 8 to 87 months, with a mean of 48 months. Doppler echocardiography, ultrafast computed tomography, and 3-dimensional aerial image studies were performed during follow-up.

RESULTS

Five of these six cases were found combined with coronary artery fistula, and the cause for these giant coronary artery aneurysms was congenital. The remaining case was caused by atherosclerosis. After surgery, all patients recovered uneventfully, without in-hospital mortality. None died during the follow-up, nor did any have recurrence of the symptoms or giant coronary artery aneurysm.

CONCLUSION

Giant coronary artery aneurysm is a rare entity that is commonly caused by congenital malformation and combined with other cardiac anomalies. An optimal surgical operation should be based on the specific cardiac anomaly of the individual patient.

摘要

目的

巨大冠状动脉瘤是一种极其罕见的疾病。既往大多数报道仅涉及个别病例。本报告描述了6例巨大冠状动脉瘤患者,探讨其病因,并旨在为这种特殊且罕见的病理情况确立最佳手术策略。

方法

1996年7月至2004年10月,共有30268例患者在北京阜外医院接受心脏手术。其中,6例被诊断为巨大冠状动脉瘤并接受了手术。对这6例患者的手术采用了多种手术策略,如冠状动脉瘤切除术、冠状动脉重建术以及同期冠状动脉搭桥术。对于合并冠状动脉瘘、主动脉瓣关闭不全或血栓等并发症的患者,同时进行了额外的手术,如瘘管闭合术、主动脉瓣置换术、主动脉成形术和栓子切除术。对患者进行了8至87个月的随访,平均随访时间为48个月。随访期间进行了多普勒超声心动图、超快速计算机断层扫描和三维航空图像研究。

结果

这6例患者中有5例合并冠状动脉瘘,这些巨大冠状动脉瘤的病因是先天性的。其余1例由动脉粥样硬化引起。术后所有患者恢复顺利,无住院死亡病例。随访期间无死亡病例,也无任何症状复发或巨大冠状动脉瘤复发。

结论

巨大冠状动脉瘤是一种罕见的疾病,通常由先天性畸形引起,并常合并其他心脏异常。最佳手术方案应根据患者个体的具体心脏异常情况制定。

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