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对罕见的左冠状动脉主干动脉瘤的临床见解

Clinical Insights Into a Rare Left Main Coronary Artery Aneurysm.

作者信息

Singtong Boone, Kapadia Kush, Aboujaoude Chris, Jain Swatam, McWhorter Yi

机构信息

Internal Medicine, HCA Mountain View Hospital, Las Vegas, USA.

Internal Medicine, HCA Healthcare: MountainView Hospital, Las Vegas, USA.

出版信息

Cureus. 2025 Jun 18;17(6):e86328. doi: 10.7759/cureus.86328. eCollection 2025 Jun.

Abstract

This case report presents a 61-year-old female with hypertension and hyperlipidemia who developed giant coronary artery aneurysms (GCAA). Coronary artery aneurysms (CAA) are rare, with GCAA being even rarer, occurring in a very small percentage of CAA cases. The etiology of GCAA remains unclear. While CAAs are often asymptomatic and discovered incidentally, they can lead to severe complications such as myocardial infarction, sudden cardiac death, or rupture. Imaging revealed a significant aneurysm in the coronary bifurcation - initially, the patient presented with atypical chest pain. Patient underwent atypical chest pain workup, including stress test, which was negative. Given the patient's age and comorbidities, the patient underwent a CT angiogram, which revealed a significant aneurysm at the coronary bifurcation into the left anterior descending (LAD) and circumflex arteries. This has been followed over a number of years with serial CT angiograms. A recent CT angiogram reveals a further increase in size of the aneurysm, almost approaching 1 cm. The patient underwent elective coronary angiography, revealing 30% stenosis in the LAD artery and other abnormalities. Given the growing size of the coronary aneurysm, the decision was made to perform surgical repair, including coronary artery bypass grafting. The patient was stabilized in the intensive care unit and was subsequently discharged.

摘要

本病例报告介绍了一名患有高血压和高脂血症的61岁女性,她患上了巨大冠状动脉瘤(GCAA)。冠状动脉瘤(CAA)较为罕见,巨大冠状动脉瘤则更为罕见,在CAA病例中所占比例极小。GCAA的病因尚不清楚。虽然冠状动脉瘤通常无症状,多为偶然发现,但它们可能导致严重并发症,如心肌梗死、心源性猝死或破裂。影像学检查显示冠状动脉分叉处有一个较大的动脉瘤——最初,患者表现为非典型胸痛。患者接受了包括负荷试验在内的非典型胸痛检查,结果为阴性。鉴于患者的年龄和合并症,患者接受了CT血管造影,结果显示在冠状动脉分叉处进入左前降支(LAD)和回旋支动脉处有一个较大的动脉瘤。多年来一直通过连续的CT血管造影对其进行跟踪观察。最近的一次CT血管造影显示动脉瘤尺寸进一步增大,几乎接近1厘米。患者接受了选择性冠状动脉造影,结果显示LAD动脉有30%的狭窄以及其他异常情况。鉴于冠状动脉瘤不断增大,决定进行手术修复,包括冠状动脉搭桥术。患者在重症监护病房病情稳定,随后出院。

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