Enhancing immune responses against a plasmid DNA vaccine encoding a FMDV empty capsid from serotype O.

Suppr

超能文献

作者信息

Li Yanmin, Aggarwal Neeraj, Takamatsu Haru-H, Sterling Catrina M A, Voyce Charlotte, Barnett Paul V

机构信息

FMD Vaccine Group, Pirbright Laboratory, Institute for Animal Health, Ash Road, Woking, Surrey GU24 0NF, UK.

出版信息

Vaccine. 2006 May 22;24(21):4602-6. doi: 10.1016/j.vaccine.2005.08.032. Epub 2005 Aug 24.

DOI:10.1016/j.vaccine.2005.08.032

PMID:16154238

Abstract

Various parameters have been examined for the improvement of immune responses induced by immunisation with foot-and-mouth disease virus (FMDV) DNA vaccine (pcDNA 3.1/P1-2A3C3D, P1) in swine. Our findings show that increasing the amount of P1 DNA plasmids and pGMCSF adjuvant plasmids induces stronger FMDV specific and neutralising antibody responses, as well as promoting cytokines IL-8 and IFNgamma secretion, in immunised pigs via multiple inoculation sites.

摘要

相似文献

Enhancing immune responses against a plasmid DNA vaccine encoding a FMDV empty capsid from serotype O.

Vaccine. 2006 May 22;24(21):4602-6. doi: 10.1016/j.vaccine.2005.08.032. Epub 2005 Aug 24.

Foot-and-Mouth Disease Virus neutralizing antibodies production induced by pcDNA3 and Sindbis virus based plasmid encoding FMDV P1-2A3C3D in swine.

Antiviral Res. 2009 Jul;83(1):45-52. doi: 10.1016/j.antiviral.2009.03.004. Epub 2009 Mar 27.

Comparison of immune responses to different foot-and-mouth disease genetically engineered vaccines in guinea pigs.

J Virol Methods. 2008 Jan;147(1):143-50. doi: 10.1016/j.jviromet.2007.08.027. Epub 2007 Oct 25.

Induction of protective immunity in swine by immunization with live attenuated recombinant pseudorabies virus expressing the capsid precursor encoding regions of foot-and-mouth disease virus.

Vaccine. 2008 May 23;26(22):2714-22. doi: 10.1016/j.vaccine.2008.03.020. Epub 2008 Apr 1.

Immune response in guinea pigs vaccinated with DNA vaccine of foot-and-mouth disease virus O/China99.

Vaccine. 2005 May 9;23(25):3236-42. doi: 10.1016/j.vaccine.2004.03.074.

Immunogenicity of plasmids encoding P12A and 3C of FMDV and swine IL-18.

Antiviral Res. 2007 Oct;76(1):59-67. doi: 10.1016/j.antiviral.2007.05.003. Epub 2007 Jun 4.

Optimization strategy for plasmid DNAs containing multiple-epitopes of foot-and-mouth disease virus by cis-expression with IL-2.

Vaccine. 2008 Feb 6;26(6):769-77. doi: 10.1016/j.vaccine.2007.11.093. Epub 2007 Dec 26.

Dramatic improvement in FMD DNA vaccine efficacy and cross-serotype antibody induction in pigs following a protein boost.

Vaccine. 2008 May 19;26(21):2647-56. doi: 10.1016/j.vaccine.2008.01.037. Epub 2008 Feb 12.

DNA vaccination against foot-and-mouth disease via electroporation: study of molecular approaches for enhancing VP1 antigenicity.

J Gene Med. 2006 Sep;8(9):1182-91. doi: 10.1002/jgm.941.

Combined DNA vaccination against three animal viruses elicits decreased immunogenicity of a single plasmid in mice.

Vaccine. 2007 May 30;25(22):4429-36. doi: 10.1016/j.vaccine.2007.03.023. Epub 2007 Mar 30.

引用本文的文献

Foot-and-mouth disease in Asia.

Virus Res. 2025 Jan;351:199514. doi: 10.1016/j.virusres.2024.199514. Epub 2024 Dec 19.

Development of Foot-and-Mouth Disease Vaccines in Recent Years.

Vaccines (Basel). 2022 Oct 28;10(11):1817. doi: 10.3390/vaccines10111817.

Foot and Mouth Disease Vaccine Development and Challenges in Inducing Long-Lasting Immunity: Trends and Current Perspectives.

Vet Med (Auckl). 2021 Sep 1;12:205-215. doi: 10.2147/VMRR.S319761. eCollection 2021.

Development of a foot-and-mouth disease virus serotype A empty capsid subunit vaccine using silkworm (Bombyx mori) pupae.

PLoS One. 2012;7(8):e43849. doi: 10.1371/journal.pone.0043849. Epub 2012 Aug 27.

Research in advance for FMD novel vaccines.

Virol J. 2011 Jun 3;8:268. doi: 10.1186/1743-422X-8-268.

Construction and immune response characterization of a recombinant pseudorabies virus co-expressing capsid precursor protein (P1) and a multiepitope peptide of foot-and-mouth disease virus in swine.

Virus Genes. 2008 Apr;36(2):393-400. doi: 10.1007/s11262-008-0204-6. Epub 2008 Feb 2.

Immunization of DNA vaccine encoding C3d-VP1 fusion enhanced protective immune response against foot-and-mouth disease virus.

Virus Genes. 2007 Oct;35(2):347-57. doi: 10.1007/s11262-007-0105-0. Epub 2007 May 12.

文献AI研究员

20分钟写一篇综述，助力文献阅读效率提升50倍。

立即体验

用中文搜PubMed

大模型驱动的PubMed中文搜索引擎

马上搜索

文档翻译

学术文献翻译模型，支持多种主流文档格式。

立即体验