Ferrero S, Petrera P, Colombo B M, Navaratnarajah R, Parisi M, Anserini P, Remorgida V, Ragni N
Department of Obstetrics and Gynaecology, San Martino Hospital and University of Genoa, Largo R.Benzi 1, 16132 Genoa, Italy.
Hum Reprod. 2005 Dec;20(12):3514-7. doi: 10.1093/humrep/dei263. Epub 2005 Sep 9.
This study aimed to investigate asthma prevalence and severity in women with and without endometriosis.
Before laparoscopy, asthma prevalence was evaluated in 879 women of reproductive age, undergoing surgery because of benign gynaecological conditions. Diagnosis of bronchial asthma was based on the American Thoracic Society criteria; asthma severity was classified in four categories according to the 2002 Global Initiative for Asthma guidelines. Asthmatic patients completed the Living with Asthma Questionnaire (LWAQ). Endometriosis was confirmed histologically and classified according to the revised American Fertility Society criteria.
There were no significant differences in age, smoking status, and other demographic and health characteristics between patients with endometriosis (n = 467) and controls (n = 412). Asthma prevalence was similar in women with (23/467, 4.9%; 95% CI, 3.1-7.3) and without (22/412, 5.3%; 95% CI, 3.4-8.0; P = 0.781) endometriosis. Asthma severity was similar in women with and without endometriosis, with 12 (52.2%) women with endometriosis and 13 (59.1%) controls being in the intermittent (mildest) degree of severity. No significant difference was observed between women with and without endometriosis in the LWAQ total score.
Women with endometriosis do not have an increased risk of having asthma.
本研究旨在调查患有和未患有子宫内膜异位症的女性的哮喘患病率及严重程度。
在腹腔镜检查前，对879名因良性妇科疾病接受手术的育龄女性进行哮喘患病率评估。支气管哮喘的诊断依据美国胸科学会标准；哮喘严重程度根据2002年全球哮喘防治创议指南分为四类。哮喘患者完成哮喘生活问卷（LWAQ）。子宫内膜异位症经组织学确诊，并根据修订后的美国生育协会标准进行分类。
子宫内膜异位症患者（n = 467）和对照组（n = 412）在年龄、吸烟状况以及其他人口统计学和健康特征方面无显著差异。患有子宫内膜异位症的女性（23/467，4.9%；95%可信区间，3.1 - 7.3）和未患子宫内膜异位症的女性（22/412，5.3%；95%可信区间，3.4 - 8.0；P = 0.781）的哮喘患病率相似。患有和未患有子宫内膜异位症的女性哮喘严重程度相似，12名（52.2%）患有子宫内膜异位症的女性和13名（59.1%）对照组女性处于间歇期（最轻度）严重程度。患有和未患有子宫内膜异位症的女性在LWAQ总分上未观察到显著差异。
患有子宫内膜异位症的女性患哮喘的风险并未增加。
