Ferrero Simone, Anserini Paola, Remorgida Valentino, Ragni Nicola
Department of Obstetrics and Gynaecology, San Martino Hospital, University of Genoa, Italy.
Eur J Obstet Gynecol Reprod Biol. 2005 Jul 1;121(1):94-8. doi: 10.1016/j.ejogrb.2004.11.019.
Previous studies did not establish a clear correlation between the presence of endometriosis and the values of body mass index (BMI).
The BMI of 366 women with endometriosis was compared to that of 248 controls undergoing laparoscopy because of benign gynaecological conditions. Significant differences at univariate analyses were confirmed by using Analysis of covariance (ANCOVA) to control for potential confounding variables.
BMI was significantly lower in women with endometriosis than in controls (p < 0.001); this difference was confirmed when the analysis was restricted to subjects with normal BMI (18.50-24.99 kg/m(2)) (p = 0.002). 4.8% of control subjects and no woman with endometriosis were obese. No significant difference was observed in the BMI of women with mild (revised classification of the American Fertility Society, rAFS I-II) and severe endometriosis (rAFS III-IV).
Women with endometriosis have lower BMI and are less frequently obese than control subjects. Further studies should investigate the physiopathological basis of decreased BMI in women with endometriosis.
既往研究未明确子宫内膜异位症的存在与体重指数（BMI）值之间的相关性。
将366例子宫内膜异位症女性的BMI与248例因良性妇科疾病接受腹腔镜检查的对照者的BMI进行比较。通过使用协方差分析（ANCOVA）控制潜在混杂变量，证实了单因素分析中的显著差异。
子宫内膜异位症女性的BMI显著低于对照组（p < 0.001）；当分析仅限于BMI正常（18.50 - 24.99 kg/m²）的受试者时，这一差异得到证实（p = 0.002）。4.8%的对照者肥胖，而子宫内膜异位症女性中无肥胖者。轻度（美国生育协会修订分类，rAFS I-II）和重度子宫内膜异位症（rAFS III-IV）女性的BMI未观察到显著差异。
与对照者相比，子宫内膜异位症女性的BMI较低，肥胖发生率也较低。进一步的研究应调查子宫内膜异位症女性BMI降低的生理病理基础。
