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[益生菌]

[Probiotics].

作者信息

Veldman A

机构信息

Veevoedkundige Mededeling van het CLO-Instituut voor de Veevoeding De Schothorst, Lelystad.

出版信息

Tijdschr Diergeneeskd. 1992 Jun 15;117(12):345-8.

PMID:1615530
Abstract

Probiotics, living cultures of micro-organisms, are currently of great interest as counterparts to antibiotics. The idea behind the use of probiotics is that the development and stability of intestinal microflora can be enhanced. The protection against infections is increased, resulting in fewer health problems and increased productivity. The mechanism of action of probiotics is not yet known, although there are several hypotheses. There is increasing evidence to suggest that probiotics act by stimulating the host's immune systems. The only accepted example of effective protection against infections provided by living micro-organism is the 'Nurmi concept', whereby one-day-old chicks acquire an enhanced protection against Salmonella infections when they are administered the complex intestinal flora of older chicks. The effects of probiotics on the growth, feed conversion or production of farm animals are, even in specific situations, not consistent enough to consider their use out of economic considerations. Probiotics are used to (re)establish the intestinal flora of patients or persons with lactose intolerance. The claims that probiotics have cholesterol-lowering and anti-tumour actions are based on animal experiments and require further investigations.

摘要

益生菌作为微生物的活培养物,目前作为抗生素的对应物备受关注。使用益生菌背后的理念是可以增强肠道微生物群的发育和稳定性。对感染的防护能力增强,从而减少健康问题并提高生产力。尽管有几种假说,但益生菌的作用机制尚不清楚。越来越多的证据表明,益生菌通过刺激宿主的免疫系统发挥作用。活微生物提供有效抗感染保护的唯一被认可的例子是“努尔米概念”,即给一日龄雏鸡投喂大龄雏鸡的复杂肠道菌群时,它们对沙门氏菌感染的防护能力会增强。即使在特定情况下,益生菌对农场动物生长、饲料转化率或生产的影响也不够一致,无法出于经济考虑而使用它们。益生菌用于(重新)建立乳糖不耐受患者或人群的肠道菌群。关于益生菌具有降低胆固醇和抗肿瘤作用的说法是基于动物实验,需要进一步研究。

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