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[生活在不同放射生态环境地区儿童外周血淋巴细胞染色体畸变的频率]

[Frequency of chromosome aberrations in peripheral blood lymphocytes of children living in regions with various radio-ecologic situations].

作者信息

Pilinskaia M A, Dybskiĭ S S

出版信息

Tsitol Genet. 1992 Mar-Apr;26(2):11-7.

PMID:1615554
Abstract

First results of cytogenetic monitoring of children, living in contaminated regions of the Ukraine show statistically significant increase in quantity of chromosome aberrations, that is positively correlated with environmental situation. The effect found shows that damage of genome stability must be accounted as an indicator of increased possibility of gene-based pathology in studied groups as compared to control.

摘要

对生活在乌克兰受污染地区儿童进行细胞遗传学监测的初步结果显示,染色体畸变数量在统计学上显著增加,这与环境状况呈正相关。所发现的这一效应表明,与对照组相比,基因组稳定性受损必须被视为研究组中基于基因的病理学可能性增加的一个指标。

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