Quietzsch J, Baumgarten C
Kinderklinik, Städtischen Kliniken Chemnitz.
Z Rheumatol. 1992 Mar-Apr;51(2):65-77.
We report a 12-year study of a family with high mortality rate due to primary generalized epilepsy. During indicated and non-indicated therapy with anticonvulsive drugs (succinimides and hydantoines) there developed symptoms of systematic lupus erythematosus. The value of controlled immunological and genetic markers is discussed.
我们报告了一项对因原发性全身性癫痫导致高死亡率的家族进行的为期12年的研究。在使用抗惊厥药物(琥珀酰亚胺类和乙内酰脲类)进行指定和非指定治疗期间,出现了系统性红斑狼疮的症状。文中讨论了受控免疫和遗传标志物的价值。