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慢性淋巴细胞白血病患者的播散性赭曲霉感染:一例病例报告及血液系统恶性肿瘤相关文献综述

Disseminated Ochroconis gallopavum infection in a chronic lymphocytic leukemia: a case report and review of the literature on hematological malignancies.

作者信息

Fukushima Noriyasu, Mannen Kotaro, Okamoto Sumiaki, Shinogi Taro, Nishimoto Katsutaro, Sueoka Eisaburo

机构信息

Department of Internal Medicine, Faculty of Medicine, Saga University, Japan.

出版信息

Intern Med. 2005 Aug;44(8):879-82. doi: 10.2169/internalmedicine.44.879.

Abstract

Disseminated fungal infection is an important cause of morbidity and mortality among patients with hematological malignancies. Ochroconis gallopavum is a dematiaceous and thermotolerant fungus that causes opportunistic infections in immunocompromised hosts. About only 30 cases of this organism infection have been reported worldwide. We report a disseminated Ochroconis gallopavum infection in a B-cell chronic lymphocytic leukemia patient. In spite of intensive anti-fungal treatment, no improvement in the clinical condition was observed and the patient died 4 months after diagnosis of the infection. Ochroconis gallopavum infection is a potentially fatal disease in hematological malignancies.

摘要

播散性真菌感染是血液系统恶性肿瘤患者发病和死亡的重要原因。鸡雏曲霉是一种暗色、耐热真菌,可在免疫功能低下的宿主中引起机会性感染。全球仅报道了约30例该菌感染病例。我们报告了1例B细胞慢性淋巴细胞白血病患者发生的播散性鸡雏曲霉感染。尽管进行了强化抗真菌治疗,但患者的临床状况未见改善,在感染诊断后4个月死亡。鸡雏曲霉感染在血液系统恶性肿瘤中是一种潜在的致命疾病。

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