Fukushima Noriyasu, Mannen Kotaro, Okamoto Sumiaki, Shinogi Taro, Nishimoto Katsutaro, Sueoka Eisaburo
Department of Internal Medicine, Faculty of Medicine, Saga University, Japan.
Intern Med. 2005 Aug;44(8):879-82. doi: 10.2169/internalmedicine.44.879.
Disseminated fungal infection is an important cause of morbidity and mortality among patients with hematological malignancies. Ochroconis gallopavum is a dematiaceous and thermotolerant fungus that causes opportunistic infections in immunocompromised hosts. About only 30 cases of this organism infection have been reported worldwide. We report a disseminated Ochroconis gallopavum infection in a B-cell chronic lymphocytic leukemia patient. In spite of intensive anti-fungal treatment, no improvement in the clinical condition was observed and the patient died 4 months after diagnosis of the infection. Ochroconis gallopavum infection is a potentially fatal disease in hematological malignancies.
播散性真菌感染是血液系统恶性肿瘤患者发病和死亡的重要原因。鸡雏曲霉是一种暗色、耐热真菌，可在免疫功能低下的宿主中引起机会性感染。全球仅报道了约30例该菌感染病例。我们报告了1例B细胞慢性淋巴细胞白血病患者发生的播散性鸡雏曲霉感染。尽管进行了强化抗真菌治疗，但患者的临床状况未见改善，在感染诊断后4个月死亡。鸡雏曲霉感染在血液系统恶性肿瘤中是一种潜在的致命疾病。
