Covarrubias Alejandra E Trasfi, González Diaz Sandra N, Cruz Alfredo Arias, Rodríguez Gabriela Galindo, Canseco González Carlos
Centro Regional de Alergia e Inmunología Clínica, Hospital Universitario, México.
Rev Alerg Mex. 2005 Mar-Apr;52(2):72-6.
Exercise-induced asthma is a transitory bronchospasm, which occurs after 6 to 8 minutes of continuous exercise. Diagnosis is done by a suggestive clinical history and by 15 to 20% post-challenge fall in FEV1. It happens in about 6 to 13% of general population, 90% of asthmatic individuals and 40% of individuals with allergic rhinitis.
To know the frequency of asthma induced by exercise in a group of asthmatic children and teenagers who went to a summer camp.
A cross-sectional, descriptive and observational study, which included 33 patients suffering from intermittent mild asthma, was based on espirometric measurements made before and after 8 minutes of continuous exercise (running). None of them had previous diagnosis of exercise-induced asthma. FEV1 greater than or equal to 15% was considered exercise-induced asthma. The test was performed at a room temperature of 73F and humidity of 40%. All patients were asymptomatic before the study and were given short-acting inhaled beta2-agonists as rescue medication, which was not administered during the 12 previous hours to the test. Data analysis was made by means of descriptive statistic.
Thirty-three children aged 8-16 years with diagnosis of asthma were studied, with an average age of 12.5 years; 42.4% were female and 57.5% male. Of the 33 patients, 6 had (18.2%) a 15% fall in FEV1 after exercise; 50% of these patients showed exercise-induced mild asthma, 33% moderate and 17% severe. At the end of the test, in six patients (100%) FEV1 increased by 15%, five minutes after the administration of a beta2-agonist.
Exercise-induced asthma is frequent among asthmatic pediatric patients, occurring in 18.8% of this study. Likelihood of having exercise-induced asthma must be deliberately investigated in all asthmatic patients, in order to establish an opportune diagnosis of this condition and provide recommendations of preventing therapy.
运动诱发性哮喘是一种短暂性支气管痉挛，在持续运动6至8分钟后发生。通过提示性临床病史以及激发试验后第一秒用力呼气量（FEV1）下降15%至20%来进行诊断。其在普通人群中发生率约为6%至13%，在哮喘患者中为90%，在过敏性鼻炎患者中为40%。
了解参加夏令营的一组哮喘儿童和青少年中运动诱发性哮喘的发生率。
一项横断面、描述性观察性研究，纳入33例间歇性轻度哮喘患者，基于连续运动（跑步）8分钟前后的肺功能测量。他们均无运动诱发性哮喘既往诊断。FEV1下降大于或等于15%被认为是运动诱发性哮喘。测试在室温73华氏度、湿度40%的环境下进行。所有患者在研究前均无症状，并给予短效吸入β2受体激动剂作为急救药物，在测试前12小时内未使用。采用描述性统计进行数据分析。
研究了33例年龄8至16岁的哮喘患儿，平均年龄12.5岁；42.4%为女性，57.5%为男性。33例患者中，6例（18.2%）运动后FEV1下降15%；其中50%的患者表现为轻度运动诱发性哮喘，33%为中度，17%为重度。测试结束时，6例患者（100%）在使用β2受体激动剂5分钟后FEV1增加了15%。
运动诱发性哮喘在哮喘儿科患者中很常见，本研究中发生率为18.8%。必须对所有哮喘患者刻意调查其发生运动诱发性哮喘的可能性，以便对该疾病进行及时诊断并提供预防性治疗建议。
