Stewart R B, Moore M T, Marks R G, Hale W E
Department of Pharmacy Practice, College of Pharmacy, University of Florida, Gainesville.
Am J Gastroenterol. 1992 Jul;87(7):859-64.
Constipation is a common and often perplexing problem for elderly people. The prevalence of self-reported constipation and factors associated with constipation were investigated in 3,166 people over age 65. Twenty-six percent of women and 15.8% of men reported recurrent constipation (p less than 0.0001). There was a significant increase in reported constipation with increasing age (p less than 0.0001). Multiple factors were found to correlate with self-reported constipation. A logistic regression model revealed 13 factors of significance in predicting constipation. The most important factors were age, sex, total number of drugs taken, pain in the abdomen, and hemorrhoids (p less than 0.0001). Specific drugs do not appear to be important factors in constipation in the elderly. Elderly people who report the use of multiple drugs, pain in the abdomen, and hemorrhoids are at increased risk for constipation.
便秘是老年人常见且常常令人困惑的问题。对3166名65岁以上的人群进行了自我报告的便秘患病率及与便秘相关因素的调查。26%的女性和15.8%的男性报告有反复便秘（p<0.0001）。报告的便秘情况随年龄增长显著增加（p<0.0001）。发现多种因素与自我报告的便秘相关。逻辑回归模型显示有13个因素对预测便秘具有显著意义。最重要的因素是年龄、性别、所服用药物的总数、腹部疼痛和痔疮（p<0.0001）。特定药物似乎不是老年人便秘的重要因素。报告使用多种药物、腹部疼痛和患有痔疮的老年人便秘风险增加。
