Barone Antonio, Crespi Roberto, Aldini Nicoló Nicoli, Fini Milena, Giardino Roberto, Covani Ugo
Department of Biophysical, Medical and Dental Sciences and Technologies, Nanoword Institute, School of Dental Medicine, University of Genova, Italy.
Int J Oral Maxillofac Implants. 2005 Jul-Aug;20(4):519-25.
Implant placement in the posterior maxilla may often be contraindicated because of insufficient bone volume and the presence of the maxillary sinus. In these situations, sinus floor lifting and grafting frequently have been proposed as the best treatment. The aim of this study was to compare histologically the use of 100% autogenous bone versus a combination of autogenous bone and corticocancellous pig bone for maxillary sinus augmentation.
Eighteen patients requiring bilateral maxillary sinus augmentation were selected for this study. Bone for grafting was harvested from the iliac crest. Each patient received 100% autogenous bone in 1 randomly selected sinus (control side) and a 1:1 mixture of autogenous bone and corticocancellous pig bone particles in the contralateral sinus (test side). Five months after the augmentation procedure, bone biopsy specimens were taken at the time of implant placement.
No complications were observed during the surgical procedures; all patients healed uneventfully. No signs or symptoms of maxillary sinus disease were observed during the 5 months after surgery. No significant differences in bone percentages were observed in the bone biopsies from test and control sides.
It could be concluded from this study that corticocancellous pig bone particles can be successfully used in a 1:1 mixture with autogenous bone from the iliac crest for maxillary sinus augmentation in cases of severely atrophic maxilla.
由于骨量不足以及上颌窦的存在,在上颌骨后部植入种植体常常是禁忌的。在这些情况下,上颌窦底提升和植骨常常被认为是最佳治疗方法。本研究的目的是从组织学角度比较100%自体骨与自体骨和皮质松质猪骨组合用于上颌窦增高的效果。
本研究选取了18例需要双侧上颌窦增高的患者。植骨材料取自髂嵴。每位患者在1个随机选择的窦(对照侧)接受100%自体骨,在对侧窦(试验侧)接受自体骨与皮质松质猪骨颗粒按1:1比例混合的材料。增高手术后5个月,在植入种植体时采集骨活检标本。
手术过程中未观察到并发症;所有患者均顺利愈合。术后5个月内未观察到上颌窦疾病的体征或症状。试验侧和对照侧骨活检标本中的骨百分比无显著差异。
从本研究可以得出结论,在严重萎缩性上颌骨病例中,皮质松质猪骨颗粒可以与来自髂嵴的自体骨按1:1比例成功混合用于上颌窦增高。