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[混合变应原加速减敏疗法在儿童重症哮喘中的价值]

[Value of accelerated hyposensitization with mixed allergens in severe childhood asthma].

作者信息

Just J, Bodart E, Pothel E, Boulé M, Grimfeld A, Tournier G

机构信息

Centre de Diagnostic et de Traitement de l'Asthme de l'Enfant, Hôpital Trousseau, Paris.

出版信息

Ann Pediatr (Paris). 1992 Apr;39(4):236-40.

PMID:1616237
Abstract

The value (in terms of decreased numbers of attacks and of hospitalizations for attacks, decreased need for asthma medications, and improved tolerance to allergens) of rush immunotherapy to a mixture of allergens was studied in children with multiple sensitizations and severe asthma (as evaluated on the number of attacks, number of hospitalizations, and dependence on corticosteroids) already receiving optimal medical therapy. Because syndromic reactions are common, rush immunotherapy should be performed in the hospital and premedication with corticosteroids may be warranted in the most severe cases.

摘要

对于已经接受最佳药物治疗的多种致敏且患有重度哮喘(根据发作次数、住院次数以及对皮质类固醇的依赖程度评估)的儿童,研究了快速免疫疗法针对混合变应原的价值(从减少发作次数和因发作而住院的次数、减少哮喘药物需求以及提高对变应原的耐受性方面)。由于综合征反应很常见,快速免疫疗法应在医院进行,在最严重的病例中可能需要使用皮质类固醇进行预处理。

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