Tarasiuk Ariel, Greenberg-Dotan Sari, Brin Yaron S, Simon Tzahit, Tal Asher, Reuveni Haim
Sleep-Wake Disorders Unit, Soroka University Medical Center, PO Box 151, Beer-Sheva, 84105 Israel.
Chest. 2005 Sep;128(3):1310-4. doi: 10.1378/chest.128.3.1310.
To investigate determinants of health-care utilization in patients with obstructive sleep apnea syndrome (OSAS).
Case-control prospective study with OSAS patients and a control group. We compared 218 patients with OSAS to those of age-, gender-, geographically-, and family physician-matched control subjects from the general population, matched 1:1 (chi2 = 0.999).
All participants were members of Clalit Health Care Services, a health maintenance organization in the southern region of Israel. All OSAS patients underwent nocturnal polysomnography studies. Indexes of health-care utilization 2 years prior to the polysomnography were analyzed.
Health-care utilization was 1.7-fold higher (p < 0.001) in the OSAS patients due to more hospitalization days (p < 0.001), consultations (p < 0.001), and cost for drugs (p < 0.05), particularly those for the cardiovascular system. In comparison to men, women consumed significantly more health-care resources (p < 0.001). OSAS patients < or = 65 of age years consumed 2.2-fold more health-care resources than control subjects (p < 0.001). Polysomnography findings and OSAS severity and body mass index (BMI) did not predict health-care utilization, using multivariate logistic regression analysis. Age > 65 (odds ratio [OR], 2.2; p < 0.04) and female gender (OR, 2.0; p < 0.05) were the leading elements predicting the most costly OSAS patients. Arbitrarily dividing the OSAS group by cost of health-care utilization, the upper 25% (n = 55) of patients who were the "most costly" consumed sevenfold more health-care resources than the lower 75% of the patients. This was due to higher comorbidity, ie, 10 to 30% more hypertension, ischemic heart disease, diabetes mellitus, and pulmonary disease.
OSAS patients are heavy users of health-care resources. Age > 65 years and female gender were the leading elements predicting the most costly OSAS patients, and not necessarily patients with a high BMI and classic OSAS severity indexes.
调查阻塞性睡眠呼吸暂停综合征(OSAS)患者医疗保健利用的决定因素。
对OSAS患者和对照组进行病例对照前瞻性研究。我们将218例OSAS患者与来自普通人群的年龄、性别、地理位置和家庭医生匹配的对照对象进行比较,匹配比例为1:1(卡方=0.999)。
所有参与者均为以色列南部地区的健康维护组织Clalit医疗服务机构的成员。所有OSAS患者均接受了夜间多导睡眠图研究。分析了多导睡眠图检查前2年的医疗保健利用指标。
由于住院天数更多(p<0.001)、会诊次数更多(p<0.001)以及药品费用更高(p<0.05),尤其是心血管系统药物费用,OSAS患者的医疗保健利用率高出1.7倍(p<0.001)。与男性相比,女性消耗的医疗保健资源显著更多(p<0.001)。年龄≤65岁的OSAS患者消耗的医疗保健资源是对照对象的2.2倍(p<0.001)。使用多变量逻辑回归分析,多导睡眠图检查结果、OSAS严重程度和体重指数(BMI)无法预测医疗保健利用率。年龄>65岁(优势比[OR],2.2;p<0.04)和女性(OR,2.0;p<0.05)是预测OSAS患者费用最高的主要因素。任意按照医疗保健利用费用将OSAS组进行划分,费用最高的前25%(n=55)患者消耗的医疗保健资源是费用较低的后75%患者的7倍。这是由于合并症更多,即高血压、缺血性心脏病、糖尿病和肺部疾病多10%至30%。
OSAS患者是医疗保健资源的高消耗者。年龄>65岁和女性是预测OSAS患者费用最高的主要因素,而不一定是BMI高和具有典型OSAS严重程度指标的患者。