Lahm George P, Selby Thomas P, Freudenberger John H, Stevenson Thomas M, Myers Brian J, Seburyamo Gilles, Smith Ben K, Flexner Lindsey, Clark Christopher E, Cordova Daniel
DuPont Crop Protection, Stine-Haskell Research Center, 1094 Elkton Road, Newark, DE 19711, USA.
Bioorg Med Chem Lett. 2005 Nov 15;15(22):4898-906. doi: 10.1016/j.bmcl.2005.08.034.
A novel class of anthranilic diamides has been discovered with exceptional insecticidal activity on a range of Lepidoptera. These compounds have been found to exhibit their action by release of intracellular Ca2+ stores mediated by the ryanodine receptor. The discovery, synthesis, structure-activity, and biological results are presented.
已发现一类新型邻氨基苯甲酰胺，对多种鳞翅目昆虫具有卓越的杀虫活性。这些化合物通过由兰尼碱受体介导释放细胞内钙库来发挥作用。本文介绍了其发现、合成、构效关系及生物学结果。
