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布法罗心血管代谢职业警察压力(BCOPS)试点研究:方法与参与者特征

The Buffalo Cardio-Metabolic Occupational Police Stress (BCOPS) pilot study: methods and participant characteristics.

作者信息

Violanti John M, Burchfiel Cecil M, Miller Diane B, Andrew Michael E, Dorn Joan, Wactawski-Wende Jean, Beighley Christopher M, Pierino Kathleen, Joseph Parveen Nedra, Vena John E, Sharp Dan S, Trevisan Maurizio

机构信息

School of Public Health and Health Professions, Department of Social and Preventive Medicine, State University of New York at Buffalo 14214-8001, USA.

出版信息

Ann Epidemiol. 2006 Feb;16(2):148-56. doi: 10.1016/j.annepidem.2005.07.054. Epub 2005 Sep 12.

Abstract

PURPOSE

The Buffalo Cardio-Metabolic Occupational Police Stress (BCOPS) study is one of the first population-based studies to integrate psychological, physiological, and subclinical measures of stress, disease, and mental dysfunction. This pilot study was undertaken to establish a methodology and descriptive results for a larger police study.

METHODS

A stratified sample of 100 officers was randomly selected from the Buffalo, NY Police Department. Salivary cortisol served as a stress biomarker. Flow mediated dilation (FMD) and carotid intima-media thickness (IMT) were performed with ultrasound. Dual Energy X-Ray Absorptiometry (DEXA) and anthropometric measures assessed body composition. Self-report measures of depression and posttraumatic stress disorder (PTSD) were obtained.

RESULTS

Recruitment attained for the study was 100%. Seventy-five percent showed a cortisol increase upon awakening, 90% a negative diurnal slope, and 77% an increased cortisol response after a high protein lunch challenge. Dexamethasone suppression was evident. FMD showed an increase in mean brachial artery diameter of 3.2% in men and 3.9% in women, and mean IMT was lower (male=0.67 mm; female=0.62 mm) compared to populations of similar age. For males, the mean body-mass index (BMI) was 29.8 kg/m2 and total body fat 23.4%. For females, the mean BMI was 26.7 kg/m2 and total body fat 31.5%. For all officers, 16% met criteria for depression; 36% reported elevated PTSD symptoms.

CONCLUSIONS

Compared to populations of similar age, police officers had slightly lower FMD, lower carotid IMT, elevated BMI, and higher reported rates of depression and PTSD. Standardized physiological and psychological data collection and descriptive results confirmed that the methodology of the study is feasible in a working police population.

摘要

目的

布法罗心血管代谢职业警察应激(BCOPS)研究是首批基于人群的研究之一,旨在整合压力、疾病和心理功能障碍的心理、生理及亚临床测量指标。开展这项试点研究是为了为一项更大规模的警察研究建立方法并得出描述性结果。

方法

从纽约州布法罗市警察局中随机抽取100名警官作为分层样本。唾液皮质醇作为应激生物标志物。采用超声进行血流介导的血管舒张功能(FMD)和颈动脉内膜中层厚度(IMT)测量。通过双能X线吸收法(DEXA)和人体测量指标评估身体成分。获取抑郁和创伤后应激障碍(PTSD)的自我报告测量结果。

结果

该研究的招募完成率为100%。75%的人醒来时皮质醇升高,90%的人昼夜斜率为负,77%的人在高蛋白午餐挑战后皮质醇反应增强。地塞米松抑制明显。FMD显示男性肱动脉平均直径增加3.2%,女性增加3.9%,与年龄相仿人群相比,平均IMT较低(男性=0.67毫米;女性=0.62毫米)。男性的平均体重指数(BMI)为29.8千克/平方米,全身脂肪为23.4%。女性的平均BMI为26.7千克/平方米,全身脂肪为31.5%。所有警官中,16%符合抑郁标准;36%报告有PTSD症状加重。

结论

与年龄相仿人群相比,警官的FMD略低、颈动脉IMT较低、BMI升高,且抑郁和PTSD报告率较高。标准化的生理和心理数据收集以及描述性结果证实,该研究方法在在职警察人群中是可行的。

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