Charles Luenda E, Gu Ja K, Violanti John M
Health Effects Laboratory Division, National Institute for Occupational Safety and Health, Centers for Disease Control and Prevention, Morgantown, WV 26505-2888, USA.
Department of Epidemiology and Environmental Health, School of Public Health and Health Professions, State University of New York at Buffalo, Buffalo, NY 14214-8001, USA.
Int J Environ Res Public Health. 2024 Apr 3;21(4):439. doi: 10.3390/ijerph21040439.
Our aim was to investigate the impact of shiftwork on changes in central retinal arteriolar equivalent (CRAE), a measure of arteriolar width, and central retinal venular equivalent (CRVE), a measure of venular width, over five years. The participants were 117 officers (72.7% men) examined at the first (2011-2014) and second (2015-2019) follow-up examinations in the Buffalo Cardio-Metabolic Occupational Police Stress study. Shiftwork data were obtained from the City of Buffalo, NY payroll records. Retinal diameters were measured using a standardized protocol. ANCOVA was used to compare mean change in CRAE and CRVE between the two examinations across shiftwork categories. Among men only, those who worked ≥70% hours on day shifts had a larger decrease in mean CRAE (-7.13 µm ± 2.51) compared to those who worked <70% day (-0.08 ± 0.96; = 0.011). Among patrol officers, those who worked ≥70% day had a larger decrease in CRAE compared to those who worked <70% day ( = 0.015). Also, officers who worked ≥70% day had an increase in mean CRVE (µm) (4.56 ± 2.56) compared to those who worked <70% (-2.32 ± 1.32; = 0.027). Over the five-year period, we observed adverse changes in arteriolar and venular diameters among officers who worked ≥70% on day shifts. The results should be interpreted with caution due to the small sample sizes.
我们的目的是研究轮班工作对视网膜中央动脉等效直径（CRAE，一种测量动脉宽度的指标）和视网膜中央静脉等效直径（CRVE，一种测量静脉宽度的指标）在五年间变化的影响。参与者为布法罗心血管代谢职业警察应激研究中在第一次（2011 - 2014年）和第二次（2015 - 2019年）随访检查时接受检查的117名警官（72.7%为男性）。轮班工作数据来自纽约州布法罗市的工资记录。使用标准化方案测量视网膜直径。采用协方差分析比较不同轮班类别在两次检查之间CRAE和CRVE的平均变化。仅在男性中，日班工作时长≥70%的人平均CRAE的下降幅度（-7.13 µm ± 2.51）大于日班工作时长<70%的人（-0.08 ± 0.96；P = 0.011）。在巡逻警官中，日班工作时长≥70%的人CRAE的下降幅度大于日班工作时长<70%的人（P = 0.015）。此外，日班工作时长≥70%的警官平均CRVE（µm）增加（4.56 ± 2.56），而日班工作时长<70%的警官则下降（-2.32 ± 1.32；P = 0.027）。在五年期间，我们观察到日班工作时长≥70%的警官的小动脉和小静脉直径出现了不良变化。由于样本量较小，这些结果应谨慎解读。
