Rival Y, Grassy G, Simeon de Buochberg M, Dusart G
Laboratoire de Chimie Organique, Faculté de Pharmacie, Illkirch, France.
Farmaco. 1992 Jan;47(1):47-61.
A series of 16 antibiotics from different classes (5-nitro imidazoles, beta-lactams, cyclins, macrolids, chloramphenicol) was examined for their bacteriostatic and bactericidal activities on 45 strains of Clostridium perfringens, with determination of MIC and MBC values. Several techniques of multivariate analysis were used in order to visualize differentiations in sensitivity profiles: Principal component analysis (PCA) and preferentially Correspondence factorial analysis (CFA). This approach revealed the efficacy of antibiotics from both general and family classifications.
