Canli T, Detmer W M, Donegan N H
Yale University, New Haven, Connecticut 06520.
Behav Neurosci. 1992 Jun;106(3):498-508. doi: 10.1037//0735-7044.106.3.498.
In two experiments using the rabbit conditioned eyeblink preparation, the conditions under which a Pavlovian conditioned stimulus (CS) potentiates or diminishes the unconditioned response (UR) were examined. The results indicated that, after discrimination training (CS+ vs. CS-), the CS+ diminished UR amplitude at the training interstimulus interval (ISI). When CS+ trials were segregated into trials on which a conditioned response (CR) did or did not occur, the CS+ diminished the UR when it elicited a CR, but not when a CR failed to occur. When the CS-unconditioned stimulus (US) interval was lengthened to 10 s, the CS+ reliably potentiated the eyeblink UR on CR trials but did not potentiate responding on trials on which a CR was absent. The results are discussed in terms of the modulatory effects and temporal properties of conditioned fear and an associatively produced decrement in US processing.
在两项使用兔条件性眨眼反应实验准备的实验中，研究了经典条件刺激（CS）增强或减弱无条件反应（UR）的条件。结果表明，在辨别训练（CS+对CS-）后，CS+在训练刺激间隔（ISI）时减小了UR幅度。当将CS+试验分为出现或未出现条件反应（CR）的试验时，CS+在引发CR时减小了UR，但在未出现CR时则没有。当CS-无条件刺激（US）间隔延长至10秒时，CS+在CR试验中可靠地增强了眨眼UR，但在没有CR的试验中没有增强反应。从条件性恐惧的调节作用和时间特性以及US加工中联合产生的递减方面对结果进行了讨论。
