Mentegazzi F, Danelli G, Ghisi D, Tosi M, Gennari A, Fanelli G
Anesthesia and Resuscitation Unit, Azienda Ospedaliera di Parma, Italy.
Minerva Anestesiol. 2005 Sep;71(9):497-9.
The introduction of low molecolar weith heparin (LMWE) and the strong antithromboembolic prophylaxis protocols used in the USA, underlined the risk of spinal hemorrhage in patients receveing a neuraxial blockade. On the other side, the efficacy of these techniques over general anesthesia doesn't allow the anesthesist to miss this pratice, where possible. So it's necessary to quantify the spinal hematoma risk in patients assuming these drugs. Unfortunately, routine investigations on coagulation factors and platelets count are not reliable if patients are receiving LMWE. Waiting for dynamic tests concerning the coagulative status such as thromboelastography (TEG), many hospitals follow many different guidelines. For these reasons peripherical nerve block techniques are a good alternative, since they are not influenced by the efficacy of the coagulation system.
低分子量肝素(LMWE)的引入以及美国所采用的强效抗血栓栓塞预防方案,突显了接受神经轴阻滞患者发生脊髓出血的风险。另一方面,这些技术相对于全身麻醉的有效性使麻醉医生在可能的情况下不会放弃这种做法。因此,有必要对使用这些药物的患者的脊髓血肿风险进行量化。不幸的是,如果患者正在接受LMWE治疗,常规的凝血因子和血小板计数检查并不可靠。在等待诸如血栓弹力图(TEG)等有关凝血状态的动态检查结果期间,许多医院遵循许多不同的指南。出于这些原因,外周神经阻滞技术是一个很好的替代选择,因为它们不受凝血系统功效的影响。