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[空肠和回肠切除对肠黏膜营养的影响。大鼠实验研究]

[The effect of resection of the jejunum and ileum on intestinal mucosal trophism. An experimental study on the rat].

作者信息

Gómez de Segura I A, De Miguel E, Góngora C, López-Bravo A, Coloma A, Rodríguez-Montes J A

机构信息

Servicio de Cirugía Experimental, Hospital La Paz, Madrid.

出版信息

Rev Esp Enferm Dig. 1992 May;81(5):317-21.

PMID:1616739
Abstract

Intestinal resection leads to anatomo-physiological adaptive changes in the small bowel depending on its localization and extension. Two 50% resection models were done, jejunal resection (55 cm.) and ileal resection (55 cm.), in the attempt to determine the trophic response of the remnant bowel from jejunal and ileal samples. Significant increases were seen in mucosal villous length, jejunal values were greater than ileal and the greatest values were when the whole ileum was conserved. No significant changes were observed in DNA contents. These data suggest the importance of the ileal segment in the intestinal adaptive process, especially on the jejunal segment, as well as the apparent end of this response two weeks after resection.

摘要

肠切除会导致小肠根据其部位和范围出现解剖生理学适应性变化。构建了两种50%切除模型,即空肠切除(55厘米)和回肠切除(55厘米),以试图确定空肠和回肠样本中残余肠段的营养反应。观察到黏膜绒毛长度显著增加,空肠的值大于回肠,且当保留整个回肠时数值最大。DNA含量未观察到显著变化。这些数据表明回肠段在肠道适应性过程中的重要性,尤其是对空肠段而言,以及切除后两周这种反应明显结束。

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