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埃塞俄比亚的主要饮食与食道癌

Staple Ethiopian diet and cancer of the oesophagus.

作者信息

Mengesha B, Ergete W

机构信息

Mexico Higher Clinic, Addis Ababa, Ethiopia.

出版信息

East Afr Med J. 2005 Jul;82(7):353-6.

PMID:16167708
Abstract

BACKGROUND

Previous reports from Ethiopia suggest that oesophageal cancers are due to thermal injury of hot food and beverages. However, in most other countries diet plays an important role.

OBJECTIVES

To investigate the association of diet and incidence of carcinoma of oesophagus in Ethiopia.

DESIGN

A prospective study.

SETTING

All adult patients, who were either referred or self referred from other health institutions, were investigated in Mexico Higher Clinic, Addis Ababa, Ethiopia.

SUBJECTS

All patients who presented for endoscopy for the duration of one year, February 1st to January 2002, were included in the study.

RESULTS

There were 902 adult patients of whom 596 (66%) were male and 306 (34%) were female. The age range was 16 to 81 with a mean of 37 and the male to female ratio was 1.95:1. Christians out-numbered Muslims. There were more merchants than office workers or peasants. Those who came from Addis Ababa were 600 (66%) and the rural patients were 302 (34%). The ethnic groupings indicated Amhara, Gurage and Oromo to be the predominant ones. Six hundred sixty two patients ate tef, 140 ate wheat and 100 ate kocho (Qocho). There were 27 specimens, which had malignant cells. Thirteen specimens failed to show malignant cells. Thirteen (13%) Qocho eaters had cancer of oesophagus, nine (6.5%) wheat eaters had cancer and only five of tef eaters (0.70%) were affected. Dysphagia was the single most common symptom with which patients presented in cases of cancer of oesophagus. Cancer of oesophagus was located in upper, middle and EG junctional area in 5, 12 and 10 patients respectively. There were 16 cases of squamous cells and 11 cases of adenocarcinoma of a total of 40 specimen taken. Thirteen specimens failed to show malignant cells.

CONCLUSION

Kocho (Qocho) eating appearsto be associated with developing cancer of the oesophagus.

摘要

背景

埃塞俄比亚此前的报告表明,食管癌是由热食和热饮造成的热损伤所致。然而,在大多数其他国家,饮食起着重要作用。

目的

调查埃塞俄比亚饮食与食管癌发病率之间的关联。

设计

一项前瞻性研究。

地点

在埃塞俄比亚亚的斯亚贝巴的墨西哥高级诊所,对所有从其他医疗机构转诊或自行前来的成年患者进行了调查。

研究对象

纳入了2002年2月1日至2003年1月1日这一年期间接受内镜检查的所有患者。

结果

共有902名成年患者,其中596名(66%)为男性,306名(34%)为女性。年龄范围为16至81岁,平均年龄为37岁,男女比例为1.95:1。基督教徒人数超过穆斯林。商人比上班族或农民多。来自亚的斯亚贝巴的患者有600名(66%),农村患者有302名(34%)。种族分组显示,阿姆哈拉族、古拉格族和奥罗莫族占主导地位。662名患者食用苔麸,140名食用小麦,100名食用科乔(乔科)。有27个标本发现了恶性细胞。13个标本未显示恶性细胞。13名(13%)食用科乔的人患有食管癌,9名(6.5%)食用小麦的人患癌,而食用苔麸的人中只有5名(0.70%)患病。吞咽困难是食管癌患者最常见的单一症状。食管癌分别位于上、中、食管胃交界区的患者有5名、12名和10名。在总共采集的40个标本中,有16例鳞状细胞癌和11例腺癌。13个标本未显示恶性细胞。

结论

食用科乔(乔科)似乎与食管癌的发生有关。

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