Kanagalingam Malini G, Forouhi Nita G, Greer Ian A, Sattar Naveed
Division of Developmental Medicine, Scotland, UK.
BJOG. 2005 Oct;112(10):1431-3. doi: 10.1111/j.1471-0528.2005.00685.x.
Whether booking body mass index (BMI) in the UK is increasing is unknown but is of clinical interest since overweight or obese pregnant women face far greater risks of pregnancy complications including pre-eclampsia and gestational diabetes. We examined booking BMI in 1990 and 2002/2004, of women with singleton pregnancies. Our analyses indicate an increase of 1 U in mean BMI over this period despite lower parity in recent years. When the model was adjusted for maternal age, parity, smoking status and deprivation category the mean BMI was 1.37 U higher in 2002/2004 than in 1990. More striking was the significant increase in the proportion of women who were obese (BMI > or = 30 kg/m2) at booking--more than twofold higher in unadjusted analysis (18.9% vs 9.4%) rising to greater than threefold higher in multivariate analysis. These findings suggest that obesity-related pregnancy complications are likely to increase with implications for both mother and child.
英国孕妇孕期首次产检时的体重指数(BMI)是否上升尚不清楚,但这具有临床研究价值,因为超重或肥胖的孕妇面临着更高的妊娠并发症风险,包括先兆子痫和妊娠糖尿病。我们研究了1990年及2002/2004年单胎妊娠女性的首次产检BMI。我们的分析表明,尽管近年来产妇的胎次较低,但在此期间平均BMI仍上升了1个单位。当对模型进行调整,纳入产妇年龄、胎次、吸烟状况和贫困类别后,2002/2004年的平均BMI比1990年高1.37个单位。更显著的是,首次产检时肥胖(BMI≥30kg/m²)女性的比例显著增加——未经调整的分析中高出两倍多(18.9%对9.4%),多变量分析中则高出三倍多。这些发现表明,与肥胖相关的妊娠并发症可能会增加,对母婴均有影响。