McManus John, Huebner Kermit
US Army Institute of Surgical Research, 3400 Rawley E. Chambers Avenue, Fort Sam Houston, TX 78234-6315, USA.
Crit Care Clin. 2005 Oct;21(4):707-18, vi. doi: 10.1016/j.ccc.2005.06.005.
Vesicants (or blister agents) are cytotoxic alkylating compounds, which are chemical agents sometimes collectively known as mustard gas or simply as mustard. Other blister agents are nitrogen mustard; sulfur mustard; lewisite, a vesicant that contains arsenic; and phosgene oxime, a halogenated oxime that possesses different properties and toxicity from the other agents. This article discusses history, toxicity, clinical presentation, and common treatment for vesicants.
发泡剂(或起泡剂)是具有细胞毒性的烷基化化合物,这些化学制剂有时统称为芥子气或简称为芥子。其他起泡剂包括氮芥;硫芥;路易氏剂(一种含砷的发泡剂);以及光气肟(一种卤代肟,其性质和毒性与其他制剂不同)。本文讨论了发泡剂的历史、毒性、临床表现和常用治疗方法。