Prives Carol, Manfredi James J
Department of Biological Sciences, Columbia University, New York, New York 10027, USA.
Mol Cell. 2005 Sep 16;19(6):719-21. doi: 10.1016/j.molcel.2005.08.024.
Despite previous assumptions that the tumor suppressor protein p53 exists primarily and functionally as a single species, recent papers document the existence and unexpected properties of numerous p53 isoforms in cells. The complexity of p53 continues to unfold.
尽管之前认为肿瘤抑制蛋白p53主要以单一形式存在并发挥功能，但最近的论文证明了细胞中存在多种p53亚型及其意想不到的特性。p53的复杂性仍在不断展现。
