Bindra M, Keegan D J, Guenther T, Lee V
Central Eye Service, Central Middlesex Hospital, London, U.K.
Orbit. 2005 Sep;24(3):211-4. doi: 10.1080/01676830590946970.
Primary cutaneous mucinous carcinoma of the eyelid is an adenocarcinoma of the eccrine glands. It is rare and locally aggressive but the prognosis following local excision, confirmed with tumour-free margins, is good. This tumour is usually described in the elderly. We present the occurrence, clinical and histological features, and management of this tumour in a young male.A 36-year-old male presented with a small cystic right lower lid lesion, which had increased in size and pigmentation over two years. He underwent excision biopsy for diagnostic purposes followed by Moh's micrographic surgical removal. The defect was repaired with an upper eyelid skin graft. A full oncological screen including whole-body computed tomography scan excluded the presence of primary mucinous carcinoma elsewhere and any metastatic spread. There has been no recurrence of tumour 18 months following excision. Ophthalmologists should be aware of the occurrence of this tumour in a younger age group than previously described. Moh's micrographic surgery is the most suitable method of treatment following exclusion of both distant primaries and metastases.
原发性眼睑皮肤黏液癌是一种小汗腺腺癌。它很罕见且具有局部侵袭性，但在切缘无肿瘤的情况下，局部切除后的预后良好。这种肿瘤通常多见于老年人。我们报告了一名年轻男性患者的这种肿瘤的发病情况、临床和组织学特征以及治疗方法。一名36岁男性患者右眼下睑出现一个小的囊性病变，在两年内大小和色素沉着增加。为明确诊断，他接受了切除活检，随后进行了莫氏显微外科手术切除。缺损用上睑皮肤移植修复。包括全身计算机断层扫描在内的全面肿瘤学检查排除了其他部位原发性黏液癌的存在以及任何转移扩散。切除术后18个月肿瘤未复发。眼科医生应意识到这种肿瘤在比先前描述的更年轻的年龄组中也会发生。在排除远处原发性肿瘤和转移后，莫氏显微外科手术是最合适的治疗方法。
