Egger Sabin, Drewe Jürgen
Abteilung für Klinische Pharmakologie & Toxikologie, Universitätsspital, Basel, Schweiz.
Herz. 2005 Sep;30(6):493-503. doi: 10.1007/s00059-005-2723-4.
New therapeutic options such as the highly active antiretroviral therapy (HAART) have significantly improved morbidity and mortality of HIV-infected patients. Consequently, age-related diseases become more manifest. In addition, HIV infection itself causes certain cardiovascular morbidity. Therefore, treatment of cardiovascular symptoms of HIV-positive patients becomes more and more important. Pharmacotherapy in these patients is complex and requires polypharmacy with drugs carrying a high risk of drug-drug interactions.
诸如高效抗逆转录病毒疗法（HAART）等新的治疗选择显著改善了HIV感染患者的发病率和死亡率。因此，与年龄相关的疾病变得更加明显。此外，HIV感染本身会导致某些心血管疾病。因此，治疗HIV阳性患者的心血管症状变得越来越重要。这些患者的药物治疗很复杂，需要联合使用多种药物，而这些药物具有很高的药物相互作用风险。
