Chen Ji, Galt James R, Case James A, Ye Jinghan, Cullom S James, Durbin Mary K, Shao Ling, Garcia Ernest V
Emory University School of Medicine, 1364 Clifton Road, Atlanta, GA 30322, USA.
J Nucl Cardiol. 2005 Sep-Oct;12(5):567-73. doi: 10.1016/j.nuclcard.2005.04.013.
Small-field-of-view (FOV) dedicated cardiac single photon emission computed tomography (SPECT) systems will frequently exhibit severe transmission scan truncation that may degrade attenuation correction (AC). This study evaluated the impact of transmission scan truncation on AC and developed automated transmission scan truncation quality control (ATSTQC) for small-FOV systems.
Small-FOV data were simulated from the data of 10 patients acquired by a full-FOV Philips Vertex system. AC images of the full- and small-FOV data were compared by mean and maximum absolute differences of myocardial counts, and differences in stress and rest severity scores were calculated by use of the Emory Cardiac Toolbox.small-FOV systems. ATSTQC was developed to identify critical truncation that significantly increased these indices and then tested with 18 independent patients. Left-side truncation resulted in significant distortion of the quantitative indices. ATSTQC, developed on the condition that left-side truncation is critical, showed high concordance with the qualitative assessment in identification of critical truncation.
Identification of left-side truncation as critical truncation is necessary to judge whether accurate AC can be obtained. The developed ATSTQC can accurately detect critical truncation and will help clinicians decide whether to use AC in a particular study.
小视野(FOV)专用心脏单光子发射计算机断层扫描(SPECT)系统经常会出现严重的透射扫描截断,这可能会降低衰减校正(AC)。本研究评估了透射扫描截断对AC的影响,并为小视野系统开发了自动透射扫描截断质量控制(ATSTQC)。
从小视野数据是由全视野飞利浦Vertex系统采集的10例患者的数据模拟而来。通过心肌计数的均值和最大绝对差值比较全视野和小视野数据的AC图像,并使用埃默里心脏工具箱计算应激和静息严重程度评分的差异。开发了ATSTQC以识别显著增加这些指标的关键截断,然后对18例独立患者进行测试。左侧截断导致定量指标出现显著失真。在左侧截断至关重要的条件下开发的ATSTQC在识别关键截断方面与定性评估具有高度一致性。
将左侧截断识别为关键截断对于判断是否能够获得准确的AC是必要的。所开发的ATSTQC能够准确检测关键截断,并将有助于临床医生决定在特定研究中是否使用AC。