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[药物与交通事故]

[Drugs and traffic accidents].

作者信息

Mravcík V, Zabranský T, Vorel F

机构信息

Národni monitorovací stiedisko pro drogy a drogové závislosti, Urad vlády CR, Praha.

出版信息

Cas Lek Cesk. 2005;144(8):550-5; discussion 555-6.

Abstract

BACKGROUND

The aim of the study was to map the prevalence of alcohol and other psychotropic substances in deceased participants of traffic accidents in the Czech Republic.

METHODS AND RESULTS

The studied sample included persons autopsied in the departments of forensic medicine and forensic toxicology that died during traffic accidents and were toxicologically tested in 2003. Case definition involved alcohol cases with blood alcohol concentration (BAC) 0,2 g/kg and higher, with cannabis, detections of active THC metabolites only were taken into account; in cases where volatile substances (solvents) were detected we included into the definition only cases with substances not produced post mortem or in some physiological or pathological statuses. We identified 554 cases of whom 440 (79.4%) were males and 114 (20.6%) were females. 35.5% were in the age group 20 - 34 years. The sample has been classified into 4 categories (average age, % of males): pedestrians (45.4, 76.2), bicyclists (51.1, 82.0), drivers (36.3, 91.2) and others (36.1, 66.2). Alcohol was tested in 548 cases, 214 (39.1%) of those were found positive. 380 cases were tested for other psychotropic substances than alcohol; samples taken from 25 bodies (6.6%) were found positive for at least for one of these substances. 8 cases were positive both for alcohol and some other psychotropic substance - i.e. 3.7% out of 214 cases positive for alcohol were positive for other substance and 32.0% out of 25 cases positive at least for any other psychotropic substance were alcohol-positive. When focusing our analysis at the active participants of road traffic accidents only - pedestrians, bicyclists and drivers (altogether 397 cases) - we have found alcohol to be tested in 394 cases, out of which 158 (39.1%) were positive; as for other psychotropic substances, 314 cases were tested and 23 (7.3%) were positive at least for one of them. 7 cases were found positive for alcohol and other psychotropic substance simultaneously; this represents 4.4% out of 158 cases positive for alcohol and 30.4% out of 23 cases positive at least for one psychotropic substance other than alcohol. Average BAC in active participants of road traffic accidents positive for alcohol were 1.81%, (1.98%o in pedestrians, 1.78 %o in bicyclists and 1.64 %o in drivers). Prevalence of either alcohol or any other psychotropic substances is the lowest in the category of drivers - with the exception of active cannabinoid compounds. Alcohol was by far the most prevalent psychotropic substance, also cannabis, benzodiazepines and stimulants have been found in not negligible frequencies.

CONCLUSIONS

The study confirms high prevalence of alcohol influence in deceased participants of traffic accidents. Prevalence of other psychotropic substances is lower by order, but it becomes also significant.

摘要

背景

本研究旨在明确捷克共和国交通事故死亡参与者中酒精及其他精神活性物质的流行情况。

方法与结果

研究样本包括2003年在交通事故中死亡并在法医学和法医毒理学部门进行尸检及毒理学检测的人员。病例定义包括血液酒精浓度(BAC)为0.2 g/kg及以上的酒精病例,大麻方面,仅考虑活性四氢大麻酚代谢物的检测结果;对于检测出挥发性物质(溶剂)的情况,仅将死后未产生或处于某些生理或病理状态下未产生的物质纳入定义范围。我们共识别出554例病例,其中440例(79.4%)为男性,114例(20.6%)为女性。35.5%的病例年龄在20 - 34岁之间。样本分为4类(平均年龄,男性比例):行人(45.4岁,76.2%)、骑自行车者(51.1岁,82.0%)、驾驶员(36.3岁,91.2%)和其他人员(36.1岁,66.2%)。对548例病例进行了酒精检测,其中214例(39.1%)呈阳性。对380例病例进行了除酒精外的其他精神活性物质检测;从25具尸体(6.6%)的样本中至少检测出一种此类物质呈阳性。8例病例酒精和其他某种精神活性物质均呈阳性——即酒精检测呈阳性的214例病例中有3.7%同时其他物质呈阳性,至少检测出一种其他精神活性物质呈阳性的25例病例中有32.0%酒精呈阳性。当仅将分析聚焦于道路交通事故的实际参与者——行人、骑自行车者和驾驶员(共397例病例)时,我们发现对394例病例进行了酒精检测,其中158例(39.1%)呈阳性;对于其他精神活性物质,检测了314例病例,其中23例(7.3%)至少有一种呈阳性。7例病例同时酒精和其他精神活性物质呈阳性;这分别占酒精检测呈阳性的158例病例中的4.4%以及至少检测出一种除酒精外的精神活性物质呈阳性的23例病例中的30.4%。道路交通事故实际参与者中酒精检测呈阳性者的平均BAC为1.81%,(行人中为1.98‰,骑自行车者中为1.78‰,驾驶员中为1.64‰)。除活性大麻素化合物外,驾驶员类别中酒精或任何其他精神活性物质的流行率最低。酒精是迄今为止最普遍的精神活性物质,大麻、苯二氮䓬类药物和兴奋剂的检出频率也不容忽视。

结论

本研究证实交通事故死亡参与者中酒精影响的流行率很高。其他精神活性物质的流行率依次较低,但也很显著。

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