Holmgren Per, Holmgren Anita, Ahlner Johan
Department of Forensic Chemistry, National Board of Forensic Medicine, University hospital, S-58185 Linköping, Sweden.
Forensic Sci Int. 2005 Jun 30;151(1):11-7. doi: 10.1016/j.forsciint.2004.06.031.
During the years 2000-2002, alcohol, pharmaceuticals and illicit drugs were analysed in blood samples from fatally injured drivers in Sweden. The total number of drivers was 920 and in 855 of these, corresponding to 93%, a toxicological investigation was performed. About 85% of the drivers were men and 15% were women. All but three women (96%) were car drivers while the corresponding figure for men was about 78% and about 13% were motorcyclists. The number of positive cases increased from 38.9% in year 2000 to 45.9% in year 2002 and alcohol was the most common drug with frequencies of 19.8%, 25.0% and 21.8% for the studied years 2000, 2001 and 2002, respectively. The median blood alcohol concentration ranged from 1.6 to 2.0mg/mL for men and from 1.2 to 1.8 mg/mL for women. There was a decrease in cases where alcohol was the only drug detected, from 52 out of 58 cases (90%) in year 2000 to 41 out of 61 cases (67%) in 2002. At the same time there was an increase, from 5.4% to 10.0% of illicit drugs, mainly amphetamine, and the cases with multiple drug intake increased from 10% to 26%. The prevalence of pharmaceuticals as the only drug or drugs detected decreased from 14.0% to 10.4% and in the majority of these cases the drug concentrations were within the therapeutic range.
在2000年至2002年期间,对瑞典致命伤司机的血液样本进行了酒精、药品和非法药物分析。司机总数为920人,其中855人,即93%,进行了毒理学调查。约85%的司机为男性,15%为女性。除三名女性(96%)外,所有女性均为汽车司机,而男性的相应比例约为78%,约13%为摩托车手。阳性病例数从2000年的38.9%增至2002年的45.9%,酒精是最常见的药物,在2000年、2001年和2002年的研究年份中,其出现频率分别为19.8%、25.0%和21.8%。男性血液酒精浓度中位数在1.6至2.0mg/mL之间,女性在1.2至1.8mg/mL之间。仅检测出酒精的病例有所减少,从2000年58例中的52例(90%)降至2002年61例中的41例(67%)。与此同时,非法药物(主要是苯丙胺)的比例从5.4%增至10.0%,多种药物摄入的病例从10%增至26%。仅检测出药品或检测出药品的病例比例从14.0%降至10.4%,在大多数此类病例中,药物浓度在治疗范围内。